Results 251 to 260 of about 1,191,146 (396)

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

Interferon Production and Protein Synthesis in Chick Cells [PDF]

, 1966
Robert M. Friedman
openalex   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source

A Novel Microencapsulated Bovine Recombinant Interferon Tau Formulation for Luteolysis Modulation in Cattle. [PDF]

Biomolecules
Lamazares E, Vásquez A, Gancino K, Sandoval F, Yáñez-Torres J, Gutierrez-Reinoso MA, García-Herreros M, Gädicke P, Cabezas I, Hugues F, Ramos TI, Camacho F, Mena-Ulecia K, Toledo JR.   +13 more
europepmc   +1 more source

Alpha-interferon induced acute renal allograft rejection [PDF]

, 1995
Holley, JL, Johnson, JP, Jordan, M, Magnone, M, McCauley, J, Scantlebury, V, Shapiro, R, Starzl, T, Vivas, C   +8 more
core  

Comparative Studies on the Production and Assay of Interferon

, 1964
George E. Gifford, Marjorie V. Mussett, E.D. Heller   +2 more
openalex   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Erratum in: Calcitonin Gene-Related Peptide Regulates Specific Interferon-Stimulating Genes to Inhibit Apoptosis of Corneal Epithelial Cells in Dry Eye Disease. [PDF]

Invest Ophthalmol Vis Sci
europepmc   +1 more source

Transcriptomic profiling of scleroderma monocytes reveals links with cardiovascular complications, implicating Notch and interferon pathways. [PDF]

J Scleroderma Relat Disord
Dinc MT, El-Adili F, Lui JK, Kripesh S, York M, Trojanowski M, Ligresti G, Lafyatis R, Trojanowska M, Bujor AM.   +9 more
europepmc   +1 more source

Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine [PDF]

, 1991
Fung, J, Gavaler, JS, Starzl, TE, Van Thiel, DH, Wright, HI   +4 more
core