Results 301 to 310 of about 1,191,146 (396)

Dysregulated type I/III interferon system in circulation from patients with anti-MDA5-positive dermatomyositis. [PDF]

Sci Rep
Yoshida A, Gono T, Okazaki Y, Shimizu M, Igarashi Y, Kitahara Y, Fujisawa T, Suda T, Yokobori S, Morita R, Kuwana M.   +10 more
europepmc   +1 more source

Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment

Advanced Science, EarlyView.
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen, Sheng‐Liang Cheng, Yu‐Ting Yen, Hsin‐Mei Lee, Te‐Haw Wu, Jane Wang, Shu‐Yi Lin, Yunching Chen   +7 more
wiley   +1 more source

Alternatively spliced isoforms of IRF7 differentially regulate interferon expression to tune response to viral infection. [PDF]

Cell Rep
Panthi A, Ferretti MB, Howard O, Pokharel SM, McCracken R, Boudreault S, Quesnel-Vallieres M, Li Q, Cherry S, Lynch KW.   +9 more
europepmc   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Translational Insights into Interferon Alpha's Effects on Immunomolecular Dynamics in Philadelphia-Negative Myeloproliferative Neoplasms. [PDF]

Cancers (Basel)
García-Delgado R, Luque-Lupiáñez E, Mora-Infante D, Ortíz-Flores RM, Cidoncha-Morcillo B, Torres-González J, Fontalba-Navas A, Escamilla-Sánchez A.   +7 more
europepmc   +1 more source

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

Advanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan, Lin Zhu, Cien Chen, Li Zhong, Houying Leung, Wei Li, Chang Xu, Xi Yao, Huan Hu, Mandi Wu, Yuxin Hou, Hin Chu, Yiran Wang, Sheng Chen, Mingyu Pan, Zongwei Cai, Ming‐liang He   +16 more
wiley   +1 more source

A Case of Advanced Urothelial Carcinoma Requiring Treatment Following a Positive Interferon-Gamma Release Assay Prior to Avelumab Administration. [PDF]

IJU Case Rep
Odagiri Y, Hiyama Y, Ishida U, Nishiyama N, Yamamoto Y, Kitamura H.   +5 more
europepmc   +1 more source

Detection of autoantibodies against exocrine pancreas by double immunodiffusion testing [PDF]

, 1990
Horbach, E., Kaiser, Doris, Otte, M., Rögener, W., Scriba, Peter Christian, Stöcker, W.   +5 more
core  

Toxicity of interferon.

BMJ, 1981
openaire   +6 more sources