Comparative therapeutic efficacy of interferon alfa-2b and combination lopinavir/ritonavir plus interferon alfa-2b against SARS-CoV-2 [PDF]
Background The outbreak of coronavirus disease 2019 (COVID-19) posed an enormous threat to public health. The use of antiviral drugs in patients with this disease have triggered people’s attentions.
Jingyuan Liu +7 more
doaj +2 more sources
Management of common autoimmune diseases in patients with myeloproliferative neoplasms treated with pegylated interferon alfa—case report, review of the literature and multidisciplinary clinical practice recommendations [PDF]
Pegylated interferons alfa are increasingly used in patients with myeloproliferative neoplasms (MPN) due to their potential disease-modifying effect. Ropeginterferon alfa-2b has been approved for patients with polycythemia vera (PV) with no symptomatic ...
Axel Rüfer +7 more
doaj +2 more sources
Episcleritis in a patient with mucosal melanoma treated with interferon alfa-2b and radiotherapy: a case report [PDF]
Background Mucosal melanoma of the head and neck is a rare malignant tumor associated with a poor prognosis. Surgery, chemotherapy, radiotherapy, and biotherapy are common strategies for treating mucosal melanoma of the head and neck.
Li Yang +3 more
doaj +2 more sources
Interferon-alpha induced obsessivecompulsive disorder in a patient with Hepatitis-C
Interferon alpha (IFN- α) is commonly used in the treatment of viral hepatitis because of its stimulating effects on the immune response. While psychiatric adverse effects such as depression, mania or psychosis that arise during interferon alpha ...
Selma Bozkurt Zincir +3 more
doaj +1 more source
Economic evaluation of first-line treatments for metastatic renal cell carcinoma: a cost-effectiveness analysis in a health resource-limited setting. [PDF]
BACKGROUND: To estimate, from the perspective of the Chinese healthcare system, the economic outcomes of five different first-line strategies among patients with metastatic renal cell carcinoma (mRCC).
Bin Wu +6 more
doaj +1 more source
Interferon-alfa in the management of cystic craniopharyngioma in children under 5 years of age
Introduction: the best therapeutic option for the management of craniopharyngioma in younger children remains controversial, ranging from complete surgical resection, partial surgical resection associated with radiotherapy and application of ...
Jose Roberto Tude Melo +3 more
doaj +1 more source
Importance of adherence for efficacy of hepatitis C combined therapy [PDF]
Introduction. Dual antiviral therapy with pegylated interferon alfa-2a and ribavirin leads do sustained elimination of hepatitis C virus infection in over 50% patients with genotypes 1 and 4 and in over 80% with genotypes 2 and 3.
Nožić Darko +5 more
doaj +1 more source
Background and Aim Ropeginterferon alfa‐2b is a novel mono‐pegylated, extra‐long‐acting interferon. It is administered infrequently and showed good tolerability and clinical activity for the chronic hepatitis B or C treatment in our previous Phase 2 ...
Chi‐Yi Chen +22 more
doaj +1 more source
Modern opportunities of interferons in treatment of children with COVID-19
Introduction. In 2020, most doctors were at the frontlines in the fight against the novel coronavirus infection (COVID-19). In the process of searching for effective etiotropic drugs, news came in that type I interferons had been successfully used for ...
Asiya I. Safina +4 more
doaj +1 more source

