Interferon alpha - Open Access .click

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Annals of Hematology, 2015
Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid leukemia (CML). Its pleiotropic mechanism of action in CML includes immune activation and specific targeting of CML stem cells. Early studies of IFNα in CML demonstrated that patients in chronic phase could attain extremely stable remissions, which correlated with ...
Moshe, Talpaz, Jessica, Mercer, Rüdiger, Hehlmann +2 more
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Interferon alpha in lymphoma

British Journal of Haematology, 1991
A number of studies are currently in progress to evaluate the use of interferon alpha, alone and in combination with conventional chemotherapy in patients with follicular lymphoma. The background to these is reviewed, together with currently available data about the potential role of interferon alpha in cutaneous T cell lymphoma.
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Induction of interferon-alpha by interferon-beta, but not of interferon-beta by interferon-alpha, in the mouse.

Virology, 1990
The antigenicity of the interferon (IFN) produced in transgenic mice carrying an extra mouse IFN-beta gene under the control of mouse metallothionein-I enhancer-promoter was examined after induction with Cd2+. Unexpectedly, IFN-alpha in addition to IFN-beta was detected in the serum.
M, Asano +4 more
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Interferon alpha