DNMT3A mutations are unlikely to affect interferon alfa treatment outcomes in patients with polycythemia vera. [PDF]
Abu-Zeinah G +8 more
europepmc +1 more source
EFFECTS OF TREATMENT WITH TEMSIROLIMUS VERSUS INTERFERON ALPHA ON SURVIVAL OF PATIENTS WITH METASTATIC RENAL CELL CARCINOMA - SINGLE-CENTER REAL-WORLD EXPERIENCE. [PDF]
Levakov I +6 more
europepmc +1 more source
Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death that Combines with Interferon Alpha Therapy for Tumor Control. [PDF]
Stinson JA +8 more
europepmc +1 more source
A pH-Responsive Poly Beta-Amino Ester Nanoparticulate Thermo-Responsive PEG-PCL-PEG Hydrogel Dispersed System for the Delivery of Interferon Alpha to the Ocular Surface. [PDF]
Abdalla Y +3 more
europepmc +1 more source
The impact of hepatitis B surface antigen seroconversion on the durability of functional cure induced by pegylated interferon alpha treatment. [PDF]
Zhang W +6 more
europepmc +1 more source
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PSORIASIS AND ALPHA-INTERFERON
Lancet, The, 1986Two patients with metastatic renal carcinoma who were treated with recombinant-DNA-derived alpha-interferon (rIFN alpha) had exacerbation of concomitant psoriasis, and another patient experienced onset of psoriasis during treatment with rIFN alpha. This suggests that interferons may participate in the pathophysiology of psoriasis.
J R Quesada, J U Gutterman
exaly +3 more sources
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
M A, Horisberger, S, Di Marco
openaire +2 more sources
Alpha interferons are biological response modifiers that regulate immune function, slow cell proliferation, and inhibit virus replication. Large supplies of purified preparations are now available for clinical trials. Common toxicity includes an influenza-like syndrome to which tolerance occurs after several doses, and chronic fatigue and anorexia that
Carol McManus Balmer, Donald C. McLeod
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