Results 171 to 180 of about 210,768 (294)

How I do it: continuous intraventricular interferon alpha infusion in pediatric patients with subacute sclerosing panencephalitis. [PDF]

Acta Neurochir (Wien)
Tengattini F, Errichiello G, Varone A, Cinalli G, Ruggiero C.   +4 more
europepmc   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Low-density granulocytes and neutrophil extracellular traps in dengue, impacts of interferon alpha and cell-free DNA. [PDF]

Sci Rep
Saisorn W, Phuengmaung P, Kaewduangduen W, Bhunyakarnjanarat T, Doi K, Chancharoenthana W, Leelahavanichkul A.   +6 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Depressive Symptome, Störungen der Befindlichkeit und Beeinträchtigung des Alltagslebens unter einer adjuvanten Therapie maligner Melanome mit Interferon-alpha [PDF]

, 2009
Horn, Martin
core  

Interferon Alfa in the treatment of B-cell chronic lymphocytic leukemia [PDF]

, 1994
Knauf, W. U., Maubach, P. A., Adolf, D., Mitrou, P. S., Emmerich, B., Ziegle-Heitbrock, H. W. L., Thiel, E., Langenmayer, Irmgard, Bergmann, L., Dietzfelbinger, H., Nerl, C.   +10 more
core   +1 more source

Interferon-alpha/beta receptor deficiency enhances susceptibility to Powassan virus infection in mice. [PDF]

Front Microbiol
Elsharkawy A, Pathak H, Dim C, Kumar M.
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A. [PDF]

Pathol Oncol Res
Ferenczi K, Nagy ZF, Istenes I, Eid H, Bödör C, Timár B, Demeter J.   +6 more
europepmc   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source