Here, we review an overall effectiveness of interferon-based preparations and interferon biosynthesis inducers for treatment of feline leukemia, as well as development of methodological approaches to improve efficacy of interferon therapy.
T. V. Moskvina +2 more
doaj +1 more source
Evaluation of the effectiveness of ARVI treatment regimen including etiotropic (enisamium iodide) and symptomatic treatment [PDF]
Aim. To assess the effectiveness of the use of the antiviral drug enisamium iodide in the complex treatment of acute respiratory viral infections (ARVI) caused by various pathogens in routine clinical practice. Materials and methods.
D. A. Lioznov +3 more
doaj +1 more source
Efficacy of interferon inducers against Chikungunya virus in vitro
Scientific relevance. To date, no specific antivirals have been approved to treat and prevent Chikungunya fever, its complications, and sequelae. Therefore, the development of therapeutic and preventive medicinal products against Chikungunya virus (CHIKV)
E. V. Otrashevskaja +4 more
doaj +1 more source
Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel +35 more
core +2 more sources
Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5. [PDF]
During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into "infectious" virus particles.
Goodbourn, S +6 more
core +3 more sources
Drug-Drug Interactions Among Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Medications [PDF]
One-fourth of individuals diagnosed with the human immunodeficiency virus concomitantly have the hepatitis C virus infection. Since the discovery of highly active antiretroviral therapy, liver complications have become the leading cause of morbidity and ...
Gandhi, Mona A. +2 more
core +2 more sources
The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.) [PDF]
The N-terminal protease of pestiviruses, N(pro) is a unique viral protein, both because it is a distinct autoprotease that cleaves itself from the following polyprotein chain, and also because it binds and inactivates IRF3, a central regulator of ...
C Achmüller +36 more
core +10 more sources
The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells [PDF]
The NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro.
Goldbach, R.W. +3 more
core +2 more sources
Laureates of the Palladin Prize of the National Academy of Sciences of Ukraine (2008, 2011) [PDF]
In 2008 Z. R. Ulberg, O. V. Karpov and S. V. Veryovka were awarded the Palladin Prize of NAS of Ukraine for the series of scientific works “Colloid-chemical and physical-biochemical aspects of the interaction of nano- and microparticles with cells as a ...
R. P. Vynogradova, V. M. Danilova
doaj +1 more source
Changes of cytocines maintenance in blood at the genitals human papilloma caused by viruses 6/11 types before treatment with interferon inducers, are revealed. Iodantipyrine raised a level in blood of α-, β-, γ-interferon, interleykin-2 more strongly and
N. V. Shperling
doaj +1 more source

