Results 21 to 30 of about 50,714 (355)

The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.) [PDF]

, 2014
The N-terminal protease of pestiviruses, N(pro) is a unique viral protein, both because it is a distinct autoprotease that cleaves itself from the following polyprotein chain, and also because it binds and inactivates IRF3, a central regulator of ...
C Achmüller, C Castanier, CA Benedict, D Hoepfner, E Dixit, E Peterhans, F Hou, HW Platta, Irina Mohorianu, JC Martinou, JE Vince, Karen L. Mossman, KE Taylor, KV Mohan, Matthew Jefferson, Matthew Whelband, MJ Killip, MR Szymanski, N Ruggli, N Zemirli, O Bauhofer, PB Lazarow, Penny P. Powell, R Higgs, RB Seth, RE Lloyd, S Chattopadhyay, S Paz, S Sharma, SA La Rocca, SM Belgnaoui, SW Tait, T Wolff, TJ Ettema, V Doceul, V Moennig, Y Li   +36 more
core   +10 more sources

Laureates of the Palladin Prize of the National Academy of Sciences of Ukraine (2008, 2011) [PDF]

The Ukrainian Biochemical Journal, 2014
In 2008 Z. R. Ulberg, O. V. Karpov and S. V. Veryovka were awarded the Palladin Prize of NAS of Ukraine for the series of scientific works “Colloid-chemical and physical-biochemical aspects of the interaction of nano- and microparticles with cells as a ...
R. P. Vynogradova, V. M. Danilova
doaj   +1 more source

The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells [PDF]

, 2008
The NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro.
Goldbach, R.W., Hemmes, J.C., Prins, M.W., Schnettler, E.   +3 more
core   +2 more sources

Influence of interferon inducer on the cytocines status the pathients with genital papillomavirus infection сaused by Human Papilloma Virus 6/11 types

Бюллетень сибирской медицины, 2009
Changes of cytocines maintenance in blood at the genitals human papilloma caused by viruses 6/11 types before treatment with interferon inducers, are revealed. Iodantipyrine raised a level in blood of α-, β-, γ-interferon, interleykin-2 more strongly and
N. V. Shperling
doaj   +1 more source

POLUDANUM’S INFLUENCE ON REPRODUCTIVE AND RESPIRATORY SYNDROME, TRANSMISSIBLE GASTROENTERITIS AND AFRICAN SWINE FEVER VIRUSES IN PRIMARY AND CONTINUOUS CELL CULTURES

Ветеринария сегодня, 2018
Today studies of the influence of interferon synthesis inducer on human and animal body is a topical issue. Interferon synthesis inducers are substances of natural or artificial origin stimulating production of body’s own interferon. One of the synthetic
D. V. Sharypova, I. Yu.  Zhukov, Ali  Mazlum, N. N. Vlasova, O. S. Puzankova, V. L. Gavrilova, A. S. Igolkin   +6 more
doaj   +1 more source

A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]

, 2020
The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan, Campisi, Judith, Ferrucci, Luigi, Holtz, Anja, Jeon, Ok Hee, Kale, Abhijit, Kuehnemann, Chisaka, Payne, Therese, Rao, Chirag, Schilling, Birgit, Shah, Samah, Sharma, Vagisha   +11 more
core   +1 more source

Interferon-Induced Sarcoidosis

JCR: Journal of Clinical Rheumatology, 2006
Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis.
Mittie K, Doyle, Ruth, Berggren, Jeanette H, Magnus   +2 more
openaire   +4 more sources

ADMINISTRATION CRITERIA FOR INTERFERON-BASED DRUGS AND ITS INDUCERS IN ACUTE RESPIRATORY INFECTIONS IN CHILDREN

Медицинская иммунология, 2014
. Interferon profile was studied in 412 children and 41 adults with acute respiratory virus infections, as well as in forty-eight healthy children and ninety-nine adults.
E. G. Golovacheva, L. W. Ossidak, E. V. Obrastsova, O. I. Afanasyeva   +3 more
doaj   +1 more source

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]

, 1994
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM, Reiner, SL, Stowring, L, Wang, ZE, Zheng, S   +4 more
core   +1 more source

TPNA10168, an Nrf-2 activator, attenuates inflammatory responses independently of Nrf2 in microglial BV-2 cells: Involvement of the extracellular-signal-regulated kinase pathway

Journal of Pharmacological Sciences, 2022
Some chemical Nrf2 inducers possess antioxidant and anti-inflammatory properties. TPNA10168, which was identified from a chemical library as a potential activator of the Keap1-Nrf2-ARE pathway, exhibits a neuroprotective effect against oxidative stress ...
Yasuhiko Izumi, Ai Tatsumoto, Naoko Horiuchi, Monami Arifuku, Momoko Uegomori, Toshiaki Kume, Yutaka Koyama   +6 more
doaj   +1 more source