Results 51 to 60 of about 37,428 (161)

Immunopathogenesis of canine chronic ulcerative stomatitis. [PDF]

, 2020
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven.
Anderson, JG, Bizikova, P, Ford, K, Jimenez, RJ, Kol, A, Murphy, BG, Stapelton, BP, Vasilatis, D, Villarreal, A   +8 more
core   +1 more source

Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion [PDF]

, 2017
Ebola virus (EBOV) protein VP35 inhibits production of interferon alpha/beta (IFN) by blocking RIG-I-like receptor signaling pathways, thereby promoting virus replication and pathogenesis.
Adolfo García-Sastre, Alexander Bukreyev, Ana Fernandez-Sesma, Benjamin C. Yen, Bersabeh Tigabu, Christopher F. Basler, Colette A. Pietzsch, Daisy W. Leung, Lorraine K. Morlock, Maria T. Sanchez-Aparicio, Noelle S. Williams, Priya Luthra, Sebastian Aguirre, Terence S. Dermody   +13 more
core   +3 more sources

Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-binding kinase 1/interferon regulatory factor-3 and p38/ATF-2

Journal of Ginseng Research, 2017
Background: Ginsenoside Rc (G-Rc) is one of the major protopanaxadiol-type saponins isolated from Panax ginseng, a well-known medicinal herb with many beneficial properties including anticancer, anti-inflammatory, antiobesity, and antidiabetic effects ...
Tao Yu, Yanyan Yang, Yi-Seong Kwak, Gwan Gyu Song, Mi-Yeon Kim, Man Hee Rhee, Jae Youl Cho   +6 more
doaj   +1 more source

Role of Kagocel® in the treatment of recurrent herpes virus infections

Клинический разбор в общей медицине
The article provides a brief overview of the conceptual approach to the treatment of genital herpesvirus infections, a review of studies on the use of the interferon inducers Kagocel® in complex therapy of genital herpes, demonstrates clinical ...
Yuliya E. Dobrokhotova, Irina N. Kononova, Tatiana A. Ogurtsova   +2 more
doaj   +1 more source

THE EFFICIENCY ASSESSMENT OF THE EXTRA PREVENTION AGAINST FLU AND OTHER RESPIRATORY ACUTE VIRAL INFECTIONS AMONG CHILDREN AIDED BY ALFA 2B INTERFERON MEDICATION

Педиатрическая фармакология, 2006
Among many medications recommended for the treatment and prevention against flu and other respiratory acute viral infections, inteferons and interferon inducers hold a special place.
M.G. Pozdnyakova, V.L. Maksakova, I.L. Kolyvanova, V.M. Nikolaeva, T.I. Krainova, S.V. Usova, M.K. Erofeeva   +6 more
doaj   +2 more sources

Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappa B, and proinflammatory cytokines [PDF]

, 2005
Human respiratory syncytial virus (HRSV) is the leading cause of serious pediatric acute respiratory tract infections, and a better understanding is needed of the host response to HRSV and its attenuated vaccine derivatives.
Spann, Kirsten M., Tran, Kim C., Collins, Peter L.   +2 more
core   +1 more source

New diagnostic and treatment perspectives of children’s hepatic lesions

Журнал инфектологии, 2014
This review presents the current possibilities of diagnosis of children’s liver disease: to define avidity of antibodies to hepatitis A, C for detection early infection, the development of non-invasive panel of serum markers of fibrosis and the ...
Yu. V. Lobzin, L. G. Goryacheva, N. V. Rogozina, N. A. Efremova, M. Ya. Kotiv, A. L. Mukomolova   +5 more
doaj   +1 more source

Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

Respiratory Research, 2005
Background Fatal human respiratory disease associated with influenza A subtype H5N1 has been documented in Hong Kong, and more recently in Vietnam, Thailand and Cambodia. We previously demonstrated that patients with H5N1 disease had unusually high serum
Poon LLM, Long HT, Chan RWY, Chan YO, Nicholls JM, Tsao SW, Chui WH, Cheung CY, Chan MCW, Guan Y, Peiris JSM   +10 more
doaj   +1 more source

Transcriptional activity of TLR/RLR receptor genes in macrophage-like cells under the influence of drugs based on acridoneacetic acid

Медицинская иммунология
Activation of Toll-like receptors (TLRs) is one of the earliest indicators of functional activation of the innate immune system. Therefore, the development of drugs that stimulate the transcription of TLR/RLR genes and at the same time are “multi-target”
A. N. Narovlyansky, V. V. Poloskov, M. V. Mezentseva, I. A. Suetina, A. V. Tsvetnov, E. Yu. Bogdanov, I. T. Fedyakina, A. L. Kovalenko, F. I. Ershov   +8 more
doaj   +1 more source

Антивирусная и интерферониндуцирующая активность новых соединений – производных индолхиноксалинов [PDF]

, 2016
Проблематика. Розробка нових препаратів з антивірусною активністю та здатністю індукувати інтерферон є актуальним завданням з огляду на стрімке поширення вірусних інфекцій, формування резистентних до існуючих антивірусних препаратів штамів вірусів ...
Bogun, T. A., Bykova, T. I., Spivak, M. Ya., Zholner, G. G., Zholobak, N. M., Бикова, Тетяна Іванівна, Богун, Т. А., Богун, Тетяна Андріївна, Быкова, Т. И., Жолнер, Л. Г., Жолнер, Лілія Григорівна, Жолобак, Н. М., Жолобак, Надія Михайлівна, Спивак, Н. Я., Співак, Микола Якович   +14 more
core   +1 more source