Selected Milestones in Antiviral Drug Development
VirusesThis review article will describe the (wide) variety of approaches that I envisaged to develop a specific therapy for viral infections: (i) interferon and its inducers, (ii) HSV, VZV and CMV inhibitors, (iii) NRTIs (nucleoside reverse transcriptase ...
Erik De Clercq
doaj +1 more source
Лечащий Врач, 2021 The results of observational non-interventional prospective study of application of kagocel for prevention of ARVI and influenza during epidemic rise of morbidity among young people were presented.
E. P. Tikhonova +2 more
doaj
Effects of Panax ginseng on Tumor Necrosis Factor-α-Mediated Inflammation: A Mini-Review
Molecules, 2011 Panax ginseng is one of the most commonly used Chinese medicines in China, Asia and Western countries. The beneficial effects of ginseng have been attributed to the biological activities of its constituents, the ginsenosides. In this review, we summarize
Davy CW Lee, Allan SY Lau
doaj +1 more source
Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers. [PDF]
Bioorg Med Chem Lett, 2020 Chu Y +5 more
europepmc +1 more source
A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562. [PDF]
, 1985 A subpopulation of low density granular lymphocytes that express the natural killer (NK) cell-associated Leu-11 antigen (IgG Fc receptor) were stimulated directly by coculture with an NK-sensitive tumor cell, K562.
Lanier, LL, Phillips, JH
core
Optimization of the therapy of ARVI and influenza in outpatient practice
Лечащий ВрачBackground. Acute respiratory viral infections are a pathology that most often occurs in outpatient therapeutic practice (about 40 million cases per year). The term acute respiratory viral infection is a collective concept and denotes a group of diseases
D. S. Sukhanov +3 more
doaj +1 more source
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells. [PDF]
, 2005 BackgroundThe recruitment of lymphocytes to secondary lymphoid organs relies on interactions of circulating cells with high endothelial venules (HEV). HEV are exclusive to these organs under physiological conditions, but they can develop in chronically ...
Galindo, María +6 more
core +1 more source
The Study of Antiviral Drugs' Activity Against The Causative Agent of Zika Fever in Cell Culture
Антибиотики и Химиотерапия, 2020 Zika virus (ZIKV) is a representative of the viruses of the genus Flavivirus in the family Flaviviridae, it belongs to the zoonotic arbovirus infections transmitted by mosquitoes of the genus Aedes.
S. Ya. Loginova +4 more
doaj
Interferon‐lambda as a new approach for treatment of allergic asthma? [PDF]
, 2011 Michael R. Edwards +2 more
core +2 more sources
Immunotropic therapy for tuberculosis infection
Терапевтический архив, 2013 The review summarizes current views on the immunopathogenesis of tuberculosis infection. It shows the leading role of a Th1 cytokine response in the formation of antituberculosis protective immunity and the impact of cytokine balance on disease outcomes.
D S Sukhanov
doaj