Results 91 to 100 of about 201,455 (289)

ANAFERON FOR KIDS: EFFECTIVENESS AND SAFETY OF THE THERAPEUTIC AND PREVENTIVE USE IN ACUTE INTESTINAL VIRAL INFECTIONS. LITERATURE REVIEW

Медицинский совет, 2016
Acute infectious diarrheal diseases by the terminology of the World Health Organization or acute intestinal infections (AII) as they are called in Russia is a large group of acute infectious diseases characterized by development in patient of the ...
O. V. SHAMSHEVA
doaj   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Clinical and epidemiologic efficacy of late interferon inductor in in the prevention of acute respiratory viral infections and influenza in 2017–2018 pre-epidemic period

Лечащий Врач, 2021
Currently, great attention is paid to prevention of influenza and acute respiratory viral infections (ARVI). This article considers results of prospective observational study in prevention of influenza and ARVI among physicians.
V. A. Petrov, N. V. Rodionova, A. V. Malyukov, O. V. Nazarochkina, M. A. Polezhaeva, O. A. Razuvaev   +5 more
doaj  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Regulation of two interferon-inducible human genes by interferon, poly(rI)·poly(rC) and viruses

, 1988
The IFI-56K and IFI-54K genes are transcriptionally stimulated when cells are treated by interferon. We have previously shown that the IFI-56K gene is in addition directly induced by poly(rI)·poly(rC), and inducer of interferon-β. Since the regulation of
Wathelet, Marc, Clauss, Isabelle M., Content, Jean, Huez, Georges   +3 more
core  

Small-Molecule Interferon Inducers. Toward the Comprehension of the Molecular Determinants through Ligand-Based Approaches

, 2016
Hepatitis C is becoming an increasingly common cause of mortality especially in the HIV-coinfected group. Due to the efficacy of interferon (IFN) based therapy in the treatment of hepatitis C, various compounds possessing IFN-inducing activity have been ...
Rino Ragno (704366), Ira Musmuca (1943971), Antonia Caroli (1312467), Silvia Simeoni (2143105)   +3 more
core   +1 more source

Interferon-induced thrombotic microangiopathy [PDF]

Blood, 2016
Although drug-induced thrombotic microangiopathy (TMA) is commonly reported, evidence for a causal association is uncommonly documented. In this issue of Blood, Kavanagh et al use multiple methods to clearly establish a causal association of type I interferon with TMA ...
openaire   +2 more sources

RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus

Cell Reports Medicine
Summary: Pregnancy disorders in patients with autoimmune diseases or viral infections are often associated with an excessive response of type I interferons.
Xiaoyu Ding, Yonggang Zhou, Xiaofeng Qiu, Xiuxiu Xu, Xinyu Hu, Jingkun Qin, Yulan Chen, Min Zhang, Jieqi Ke, Zhenbang Liu, Ying Zhou, Chen Ding, Nan Shen, Zhigang Tian, Binqing Fu, Haiming Wei   +15 more
doaj   +1 more source

Evaluation of preventive effects of interferon inducer against acute respiratory viral infections in young people

Лечащий Врач, 2021
The results of observational non-interventional prospective study of application of kagocel for prevention of ARVI and influenza during epidemic rise of morbidity among young people were presented.
E. P. Tikhonova, T. Yu. Kuzmina, Yu. S. Kalinina   +2 more
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