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[Type I interferons].

Virologie (Montrouge, France)
Type I interferons (IFNa/b) form a family of related cytokines that include INFa, b, e/s, j, x (human) and limitin (mouse). These cytokines exert a potent antiviral activity, control cell proliferation and modulate the immune response. They are used in the fight against viral infections, tumors, and multiple sclerosis.
S, Delhaye   +4 more
openaire   +1 more source

Structure-activity of type I interferons

Biotherapy, 1997
Type I IFNs constitute a family of proteins exhibiting high homology in primary, secondary, and tertiary structures. They interact with the same receptor and transmit signals to cellular nucleus through a similar mechanism, eliciting roughly homogeneous biological activity.
openaire   +2 more sources

The Type I Interferon Pathway

Science's STKE, 2003
The type I interferon (IFN-α/β) signal transduction pathway is not only the first-characterized Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, but one of the best studied in molecular detail. IFN-α-stimulated gene factor 3 (ISGF3) is atypical for STAT-containing complexes, because it requires interaction with an ...
D. S. Aaronson, C. M. Horvath
openaire   +1 more source

The interferon type I signature is present in systemic sclerosis before overt fibrosis and might contribute to its pathogenesis through high BAFF gene expression and high collagen synthesis

Annals of the Rheumatic Diseases, 2015
Z. Brkić   +15 more
semanticscholar   +1 more source

Chicken Interferon Type I Inhibits Infectious Bronchitis Virus Replication and Associated Respiratory Illness

Journal of Interferon and Cytokine Research, 2001
Jianwu Pei   +4 more
semanticscholar   +1 more source

An overview of real‐world data sources for oncology and considerations for research

Ca-A Cancer Journal for Clinicians, 2022
Lynne Penberthy   +2 more
exaly  

Interferon type I and type II responses in an Atlantic salmon (Salmo salar) SHK-1 cell line by the salmon TRAITS/SGP microarray.

Physiological Genomics, 2007
S. Martin   +11 more
semanticscholar   +1 more source

280 ADAR1 mutations drive an interferon type I dependent psoriasis subtype

Journal of Investigative Dermatology
F. Assan   +9 more
semanticscholar   +1 more source

Health insurance status and cancer stage at diagnosis and survival in the United States

Ca-A Cancer Journal for Clinicians, 2022
Jingxuan Zhao   +2 more
exaly  

Is flavivirus resistance interferon type I‐independent?

Immunology and Cell Biology, 2003
N. Urosevic
semanticscholar   +1 more source

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