Results 101 to 110 of about 80,233 (311)

Metapneumovirus infection in children in modern conditions: clinical and immunological parallels

Детские инфекции (Москва)
Aim. The study of metapneumovirus infection clinical and immunological features in children of different ages. Patients and methods. An analysis of 22 patients with mono-metapneumovirus infection is presented.
O. P. Popova, S. V. Trushakova, I. M. Fedorova, S. I. Koteleva, S. V. Bunin, Ju. V. Shvetsova, R. V. Vartyanyan, I. G. Lyubeznova   +7 more
doaj   +1 more source

Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo

mBio, 2017
Yellow fever virus (YFV) is an arthropod-borne flavivirus, infecting ~200,000 people worldwide annually and causing about 30,000 deaths. The live attenuated vaccine strain, YFV-17D, has significantly contributed in controlling the global burden of yellow
Florian Douam, Yentli E. Soto Albrecht, Gabriela Hrebikova, Evita Sadimin, Christian Davidson, Sergei V. Kotenko, Alexander Ploss   +6 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Type I interferons cluster region studied on chromosome 9p22. [PDF]

, 2012
Type I interferons cluster region studied on chromosome 9p22.
Melanie Bevier (117596), Andreas Brandt (117599), Justo Lorenzo Bermejo (117602), Antje Sucker (117606), Iris Moll (117608), Dirk Schadendorf (103684), Eduardo Nagore (117612), Dolores Planelles (117609), Kari Hemminki (76996), Romina Elizabeth Lenci (117593), Rajiv Kumar (117613), Celia Requena (117611)   +11 more
core   +1 more source

The Effect of Interferon, Interferon Inducers or Interferon Induced Virus Resistance on Subsequent Interferon Production

Journal of General Virology, 1972
Summary The pre-treatment of mouse L cells with interferon or polyinosinic-polycytidylic acid potentiated the interferon response of these cells to subsequent stimulation with suboptimal doses of polyinosinic-polycytidylic acid. This potentiation was manifested as an earlier production of interferon, a faster attainment of maximum interferon production,
S A, Margolis, H, Oie, H B, Levy
openaire   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

What are the Roles of Interferons in Physiological Conditions? [PDF]

, 1988
Interferon was discovered in 1957 as a natural antiviral substance. Since then other interferons have been described, and their antiproliferative and immunomodulatory effects are now being exploited in clinics.
V Bocci
core   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Interferons and inflammasomes: cooperation and counterregulation in disease [PDF]

, 2016
Interferons and the IL-1 family of cytokines have important roles in host defense against invading viruses and bacteria. Inflammasomes, multimeric cytosolic sensors of infection, are required for IL-1β and IL-18 processing and release. Interferons, IL-1β,
Lauterbach, Mario A.R., Labzin, Larisa I., Latz, Eicke   +2 more
core   +1 more source

Threonine Phosphorylation and the Yin and Yang of STAT1: Phosphorylation-Dependent Spectrum of STAT1 Functionality in Inflammatory Contexts

Cells
Threonine phosphorylation promotes inflammatory functions of STAT1 while restricting its interferon (IFN) signaling in innate immune responses. However, it remains unclear whether the restriction of STAT1-mediated IFN signaling conferred by threonine ...
Maha M. Elbrashy, Hozaifa Metwally, Shuhei Sakakibara, Tadamitsu Kishimoto   +3 more
doaj   +1 more source