Results 81 to 90 of about 87,441 (309)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Role of type I interferons in inflammasome activation, cell death and disease during microbial infection [PDF]

open access: yes, 2013
Interferons were discovered over a half-century ago as antiviral factors. The role of type I interferons (IFNs) has been studied in the pathogenesis of both acute and chronic microbial infections.
R. K. Subbarao Malireddi   +3 more
core   +1 more source

Recombinant Interferon-Beta-1a Plus Ribavirin for the Treatment of Chronic HCV Infection: A Prospective, Randomized, Comparative Pilot Study

open access: yesGut and Liver, 2009
Background/Aims: Interferon beta (IFN-Ղ) has been shown to have antiviral activity, and thus could be useful in treating viral infections. Therefore, we compared the efficacy and safety of recombinant IFN-Ղ (IFN-Ղ-1a) plus oral ribavirin versus ...
doaj   +1 more source

Interferons and their potential in the treatment of ocular inflammation

open access: yes, 2009
Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Zürich ...
Regina Max   +2 more
core  

Molecular characterization and antiviral analyses of porcine type III interferons [PDF]

open access: yes, 2010
Type III interferons (IFNs) are a family of recently identified antiviral cytokines. One to 3 paralogs have been identified in several species; however, little information is available about type III IFNs in pigs.
Rowland, Raymond R. R.   +5 more
core   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

Interferons

open access: yes, 1992
LR: 20061107; PUBM: Print; JID: 7501160; 9008-11-1 (Interferons); 9035-51-2 (Cytochrome P-450 Enzyme System); CON: JAMA. 1991 Sep 11;266(10):1375-83.

core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

How cells respond to interferons.

open access: yes, 2010
How cells respond to Interferons is necessary to designe more intelligent administration of this ...
ALTAVILLA, Giuseppe   +2 more
core  

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