Results 61 to 70 of about 970,162 (283)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A recursive Riccati interior-point method for chance-constrained stochastic model predictive control

open access: yesSICE Journal of Control, Measurement, and System Integration, 2023
This study covers the model predictive control of linear discrete-time systems subject to stochastic additive disturbances and state chance constraints.
Jingyu Zhang, Toshiyuki Ohtsuka
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

A full Nesterov-Todd step interior-point method for circular cone optimization

open access: yesCommunications in Combinatorics and Optimization, 2016
In this paper‎, ‎we present a full Newton step feasible‎ ‎interior-point method for circular cone optimization by using‎ ‎Euclidean Jordan algebra‎. ‎The search direction is based on the‎ ‎Nesterov-Todd scaling scheme‎, ‎and only full-Newton step is ...
Behrouz Kheirfam
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Convex Optimization Methods for Dimension Reduction and Coefficient Estimation in Multivariate Linear Regression [PDF]

open access: yes, 2008
In this paper, we study convex optimization methods for computing the trace norm regularized least squares estimate in multivariate linear regression. The so-called factor estimation and selection (FES) method, recently proposed by Yuan et al.
Lu, Zhaosong   +2 more
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Generation of Pareto optimal solutions for multi-objective optimization problems via a reduced interior-point algorithm

open access: yesJournal of Taibah University for Science, 2018
In this paper, a reduced interior-point (RIP) algorithm is introduced to generate a Pareto optimal front for multi-objective constrained optimization (MOCP) problem.
B. El-Sobky, Y. Abo-Elnaga
doaj   +1 more source

A Quantum Interior Point Method for LPs and SDPs

open access: yes, 2018
We present a quantum interior point method with worst case running time $\widetilde{O}(\frac{n^{2.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for SDPs and $\widetilde{O}(\frac{n^{1.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for LPs, where the output
Kerenidis, Iordanis, Prakash, Anupam
core  

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