Results 61 to 70 of about 971,996 (282)
Journal of Applied Mathematics, 2013 Recently, various methods have been developed for solving linear programming problems with fuzzy number, such as simplex method and dual simplex method.
Yi-hua Zhong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A recursive Riccati interior-point method for chance-constrained stochastic model predictive control
SICE Journal of Control, Measurement, and System Integration, 2023 This study covers the model predictive control of linear discrete-time systems subject to stochastic additive disturbances and state chance constraints.
Jingyu Zhang, Toshiyuki Ohtsuka
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Computing Weighted Analytic Center for Linear Matrix Inequalities Using Infeasible Newton’s Method
Journal of Mathematics, 2015 We study the problem of computing weighted analytic center for system of linear matrix inequality constraints. The problem can be solved using Standard Newton’s method.
Shafiu Jibrin
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A Quantum Interior Point Method for LPs and SDPs
, 2018 We present a quantum interior point method with worst case running time $\widetilde{O}(\frac{n^{2.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for SDPs and $\widetilde{O}(\frac{n^{1.5}}{\xi^{2}} \mu \kappa^3 \log (1/\epsilon))$ for LPs, where the output
Kerenidis, Iordanis, Prakash, Anupam
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