Results 41 to 50 of about 17,750,041 (269)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Primal-dual Interior-Point Methods for Self-Scaled Cones [PDF]
, 1995 Primal-dual Interior-Point Methods for Self-Scaled ...
Todd, M. J., Yu. E. Nesterov
core +5 more sources
AlgorithmsAlthough interior-point methods (IPMs) have transformed mathematical programming since 1984, the original projective Karmarkar algorithm is rarely documented step by step on reproducible engineering examples that combine algorithmic transparency with ...
José Flores-Salinas +7 more
doaj +1 more source
On the simplex, interior-point and objective space approaches to multiobjective linear programming
Journal of Algorithms & Computational Technology, 2021 Most Multiple Objective Linear Programming (MOLP) algorithms working in the decision variable space, are based on the simplex algorithm or interior-point method of Linear Programming.
Paschal B Nyiam, Abdellah Salhi
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
A decomposition-based warm-start method for stochastic programming [PDF]
, 2013 In this paper we propose a warm-start technique for interior point methods applicable to multi-stage stochastic linear programming problems. The main idea is to generate an initial point by decomposing the problem at the second stage and using an ...
Colombo, Marco +3 more
core +1 more source
Detecting Infeasibility in Infeasible-Interior-Point Methods for Optimization [PDF]
, 2003 Detecting Infeasibility in Infeasible-Interior-Point Methods for ...
Todd, M. J.
core +5 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Full-Newton step infeasible-interior-point algorithm for P*(k)-horizontal linear complementarity problems [PDF]
Yugoslav Journal of Operations Research, 2015 In this paper we generalize an infeasible interior-point method for linear optimization to horizontal linear complementarity problem (HLCP). This algorithm starts from strictly feasible iterates on the central path of a perturbed problem that is
Asadi S., Mansouri H.
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source