Results 51 to 60 of about 17,750,041 (269)

Constraint Consensus Methods for Finding Interior Feasible Points in Second-Order Cones

open access: yesJournal of Applied Mathematics, 2010
Optimization problems with second-order cone constraints (SOCs) can be solved efficiently by interior point methods. In order for some of these methods to get started or to converge faster, it is important to have an initial feasible point or near ...
Anna Weigandt   +2 more
doaj   +1 more source

Tutorial on the Robust Interior Point Method

open access: yesCoRR, 2021
We give a short, self-contained proof of the interior point method and its robust version.
Yin Tat Lee, Santosh S. Vempala
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

A recursive Riccati interior-point method for chance-constrained stochastic model predictive control

open access: yesSICE Journal of Control, Measurement, and System Integration, 2023
This study covers the model predictive control of linear discrete-time systems subject to stochastic additive disturbances and state chance constraints.
Jingyu Zhang, Toshiyuki Ohtsuka
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

An infeasible interior-point method for the $P_*$-matrix linear complementarity‎ ‎problem based on a trigonometric kernel function with full-Newton‎ ‎step

open access: yesCommunications in Combinatorics and Optimization, 2018
An infeasible interior-point algorithm for solving the‎ ‎$P_*$-matrix linear complementarity problem based on a kernel‎ ‎function with trigonometric barrier term is analyzed‎.
B‎. ‎Kheirfam, M‎. ‎Haghighi
doaj   +1 more source

Bird biodiversity assessments in temperate forest: the value of point count versus acoustic monitoring protocols [PDF]

open access: yesPeerJ, 2015
Effective monitoring programs for biodiversity are needed to assess trends in biodiversity and evaluate the consequences of management. This is particularly true for birds and faunas that occupy interior forest and other areas of low human population ...
Brian T. Klingbeil, Michael R. Willig
doaj   +2 more sources

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