Results 41 to 50 of about 1,050,523 (298)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
АрхитектонThe study of various approaches to small-sized apartment designing developed by German architects in the 1920s expands the modern understanding of the concepts of social housing in Weimar Germany.
Obukhova Yulia S.
doaj +1 more source
Sunlight and Atmosphere in the Ark of the Lord Church in Krakow
Technical Transactions, 2019 The article presents the relationship between sunlight and the atmosphere of the architecture of the Ark of the Lord Church in Krakow and outlines the history of this church.
Stec Barbara
doaj +1 more source
, 2000 A Pyramid: a hierarchy of Region Adjacency Graphs (RAG) has only one type of edge "to be neighbor with". We want to add some new types of edge. The relation "to be inside" is already present as a special case of the neighborhood relation. We detail the difference between a neighborhood relation and an interior relation. Then we show that some new types
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A Topology of Everyday Constellations de Georges Teyssot
Cuadernos de Proyectos Arquitectónicos, 2019 Resumen En el libro, A topology of everyday constellations, Georges Teyssot expone los temas que va persiguiendo hace décadas, manteniendo su ya conocido registro erudito y denso. Como un flâneur intenta desentrañar la espesura compleja de las tramas de
Ana Sofía Pereira
doaj
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source