Results 51 to 60 of about 1,050,523 (298)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2019 The Ministry of the Interior coordinates preventive work against violent extremism nationally, and the work is divided between several actors. The current National Action Plan for the Prevention of Violent Radicalisation and Extremism from 2016 lists the
Kinnunen, Samuli, Partanen, Elli
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Fostering social responsibility for interior design practice [PDF]
, 2002 Tertiary interior design courses incorporating the equivalent of four years education aim to provide students with the opportunity to develop the knowledge, skills and values needed to practice as professional interior designers.
Franz, Jill M.
core
Choreography and interior design; using performance terminology to describe interior experience [PDF]
, 2018 This qualitative thesis is based on literature in two fields to establish a connection between interior design and choreography. The discipline of interior design and the field of performing arts, specifically dance, are here correlated in order to show ...
Lloyd, Maricel
core +1 more source
Between home and flight: interior space, time and desire in the films of Chantal Akerman
Journal of Aesthetics & Culture, 2021 This article sets out to review the films of Chantal Akerman, mainly those that she made in the 1970s and 1980s, observing how her filmmaking formulates a journey to and from the home against the background of the historical scene post 1968.
Irene Valle Corpas
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Comparison of the interior characteristics of Slovak warmblood horses and Lipizzan horses [PDF]
Journal of Central European Agriculture, 2018 One of the important factors that significantly affects the intensity and content of training and determines the performance it the horse interior. Character and temperament traits are described in the breeding goals of each breed of horse.
Michaela HORNÁ +3 more
doaj +1 more source