Results 51 to 60 of about 278,837 (268)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

SupaVenezia From SupaStore: Between Art, Commerce, and Spatial Dynamics

open access: yesInteriority
This exhibition review reflects on the spatial and curatorial concepts, interior spatial qualities, and precedent design processes of SupaVenezia, which was held at the A plus A Gallery in Venice from 31 August to 25 September 2022.
Ayman Kassem
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Ökompakt 50 - ventilator with heat regenerate [PDF]

open access: yesActa Montanistica Slovaca, 2000
In the paper presents ventilator with heat regenerate. The apparaturs are manufactured by f. Hölter, GmbH, and it patent schould. The quality aur in interier is on line relation to different alergical disease (Sick Building Syndrom - SBS).Ventilator with
Heinz Hölter
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Peculiarities of Operator Shooting of Television Programs in Interiors

open access: yesВісник Київського національного університету культури і мистецтв. Серія: Аудіовізуальне мистецтво і виробництво
The purpose of the research is to examine the distinctive characteristics of the process of filming television programmes in the interior and their impact on visual art and audience perception.
Баталіна Христина   +1 more
doaj   +1 more source

THE SPECIFICS OF POSTEMBUONIC BIOGENESIS OF VISTAR WHITE MICE UNDER THE EFFECT OF NITROUS OXIDES

open access: yesНаука. Инновации. Технологии, 2022
The article presents the data on the growth and development of Vistar white mice, their hematologis indices and natural resistance in the conditions of nitrous oxides effect.
Viktor Mikhailovich Ivanov
doaj  

Sensorial Interior: Museum Diorama as Phenomenal Space

open access: yesInteriority, 2018
Museum dioramas are widely recognised as historic visual tropes used to frame the grandeur of the outside world within an interior viewing space. With the development of digital technologies, data projection and soundscape have increasingly replaced ...
Sarah Edwards
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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