Results 61 to 70 of about 5,566,782 (273)
Ingeniería e Investigación, 2009 En este artículo se presenta una metodología de solución para el problema de planeamiento de la expansión de redes de trans- misión de energía eléctrica considerando contingencias simples (N-1).
Ricardo Andrés Bolaños Ocampo +2 more
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Six-point functions and collisions in the black hole interior
Journal of High Energy Physics, 2021 In the eternal AdS black hole geometry, we consider two signals sent from the boundaries into the black hole interior shared between the two asymptotic regions.
Felix M. Haehl +2 more
doaj +1 more source
Interior Point Methods for Massive Support Vector Machines [PDF]
, 2000 We investigate the use of interior point methods for solving quadratic programming problems with a small number of linear constraints where the quadratic term consists of a low-rank update to a positive semi-de nite matrix. Several formulations of the
Ferris, Michael, Munson, Todd
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
An adaptive long step interior point algorithm for linear optimization [PDF]
, 2010 summary:It is well known that a large neighborhood interior point algorithm for linear optimization performs much better in implementation than its small neighborhood counterparts. One of the key elements of interior point algorithms is how to update the
Salahi, Maziar
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Optimal Load Shedding in Deregulated System and Consideration of Effective Factors by Using a Predictor-Corrector Interior-Point Method (IPM) [PDF]
Journal of Intelligent Procedures in Electrical Technology, 2010 In this paper, intifially an introduction is presented about Electric Power market in deregulated system and load shedding by interior-point method in these systems. Then, predictor-corrector of IPM is considered and by consideration of the IEEE 6 busbar
Mojtaba Afshari, Saeed Abazari
doaj