Results 31 to 40 of about 15,567,526 (268)

Solving large scale linear programming [PDF]

open access: yes, 1993
The interior point method (IPM) is now well established as a competitive technique for solving very large scale linear programming problems. The leading variant of the interior point method is the primal dual - predictor corrector algorithm due to ...
Levkovitz, R, Mitra, G, Hafsteinsson, H
core   +6 more sources

Improving complexity of Karmarkar's approach for linear programming

open access: yesJournal of Numerical Analysis and Approximation Theory, 2014
In this paper, we are interested in the performance of Karmarkar's projective algorithm for linear programming. Based on the work of Schrijver, we offer a new displacement step better than Schrijver's one which led to a moderate improvement in the ...
Djamel Benterki, Mousaab Bouafia
doaj   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Homotopy Method for a General Multiobjective Programming Problem under Generalized Quasinormal Cone Condition

open access: yesAbstract and Applied Analysis, 2012
A combined interior point homotopy continuation method is proposed for solving general multiobjective programming problem. We prove the existence and convergence of a smooth homotopy path from almost any interior initial interior point to a solution of ...
X. Zhao   +3 more
doaj   +1 more source

Novel High-Precision and High-Robustness Localization Algorithm for Underwater-Environment-Monitoring Wireless Sensor Networks

open access: yesJournal of Marine Science and Engineering, 2023
In marine ecological environment monitoring, the acquisition of node location information is crucial, and the absence of location information can render the collected data meaningless.
Junling Ma   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A new full-NT step interior-point method for circular cone optimization

open access: yesCroatian Operational Research Review, 2019
We present a full step interior-point algorithm for circular coneoptimization using Euclidean Jordan algebras. The specificity of ourmethod is to use a transformation similar to that introduced byDarvay and Tak\'acs for the centering equations of the ...
Behrouz Kheirfam
doaj   +1 more source

A Novel Market Clearing and Safety Checking Method for Multi-Type Units That Considers Flexible Loads

open access: yesEnergies, 2020
Flexible loads have flexibility and variability in time and space, and they have been widely studied by scholars. However, the research on the participation of flexible loads in market clearing and safety checking is still insufficient.
Dong Hua, Wutao Chen, Cong Zhang
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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