Results 61 to 70 of about 970,333 (280)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
IEEE Access, 2023 One of the primary challenges in solving the State Estimation (SE) problem in low voltage networks is the presence of Gross Errors (GE). If the SE model fails to accurately estimate state variables in the presence of GE, the system operator may receive a
Yassine Boukili +4 more
doaj +1 more source
A distributed primal-dual interior-point method for loosely coupled problems using ADMM [PDF]
, 2015 In this paper we propose an efficient distributed algorithm for solving loosely coupled convex optimization problems. The algorithm is based on a primal-dual interior-point method in which we use the alternating direction method of multipliers (ADMM) to ...
Annergren, Mariette +3 more
core
A Still Simpler Way of Introducing the Interior-Point Method for Linear Programming
, 2015 Linear programming is now included in algorithm undergraduate and postgraduate courses for computer science majors. We give a self-contained treatment of an interior-point method which is particularly tailored to the typical mathematical background of CS
Mehlhorn, Kurt, Saxena, Sanjeev
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The location of supports under the monolithic reinforced concrete slabs optimization
Magazine of Civil Engineering, 2021 We consider the problem of finding the optimal location of point supports under a monolithic reinforced concrete floor slab, which provides the minimum of the objective function.
Chepurnenko Anton +3 more
doaj +1 more source
Network coding with periodic recomputation for minimum energy multicasting in mobile ad-hoc networks [PDF]
, 2009 We consider the problem of minimum-energy multicast using network coding in mobile ad hoc networks (MANETs). The optimal solution can be obtained by solving a linear program every time slot, but it leads to high computational complexity.
Effros, Michelle +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source