Results 61 to 70 of about 16,640,145 (271)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

An interior point algorithm for computing equilibria in economies with incomplete asset markets [PDF]

open access: yes, 2004
Computing equilibria in general equilibria models with incomplete asset (GEI) markets is technically difficult. The standard numerical methods for computing these equilibria are based on homotopy methods.
Esteban-Bravo, Mercedes
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

An Interior-Point algorithm for Nonlinear Minimax Problems [PDF]

open access: yes
We present a primal-dual interior-point method for constrained nonlinear, discrete minimax problems where the objective functions and constraints are not necessarily convex.
E. Obasanjo, G. Tzallas-Regas, B. Rustem
core  

A full-modified-Newton step infeasible interior-point method for monotone linear complementarity problem

open access: yesپژوهش‌های ریاضی, 2021
By using a new search direction, we propose an infeasible interior-point method for monotone linear complementarity problem. The algorithm uses only one feasibility step in each iteration, and we prove that it suffices in order to obtain a polynomial ...
Nezameddin Mahdavi-Amiri   +1 more
doaj  

Interior Point Methods in Function Space [PDF]

open access: yesSIAM Journal on Control and Optimization, 2005
A primal-dual interior point method for optimal control problems is considered. The algorithm is directly applied to the infinite-dimensional problem. Existence and convergence of the central path are analyzed, and linear convergence of a short-step path-following method is established.
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

An interior-point method for nonlinear optimization problems with locatable and separable nonsmoothness

open access: yesEURO Journal on Computational Optimization, 2015
Many real-world optimization models comprise nonconvex and nonsmooth functions leading to very hard classes of optimization models. In this article, a new interior-point method for the special, but practically relevant class of optimization problems with
Martin Schmidt
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

An infeasible-interior-point method for the \(P_\ast(k)\) -matrix LCP

open access: yesJournal of Numerical Analysis and Approximation Theory, 1998
Not available.
Jun Ji, Florian A. Potra
doaj   +2 more sources

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