Results 251 to 260 of about 277,845 (282)

The Seminal Role of the Proinflammatory Cytokine IL-1β and Its Signaling Cascade in Glioblastoma Pathogenesis and the Therapeutic Effect of Interleukin-1β Receptor Antagonist (IL-1RA) and Tolcapone. [PDF]

Int J Mol Sci
Narasimhappagari J, Liu L, Balasubramaniam M, Ayyadevara S, Aboud O, Griffin WST.   +5 more
europepmc   +1 more source

Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro. [PDF]

Stem Cell Reports
Flores-Gomez D, Hobo W, van Ens D, Kessler EL, Novakovic B, Schaap NPM, Rijnen WHC, Joosten LAB, Netea MG, Riksen NP, Bekkering S.   +10 more
europepmc   +1 more source

The Activity of Protectin DX, 17 HDHA and Leukotriene B4 Is Correlated with Interleukin-1β (IL-1β) and Interleukin-1 Receptor Antagonist (IL-1Ra) in the Early Subacute Phase of Stroke. [PDF]

Int J Mol Sci
Kotlega D, Drozd A, Zembron-Lacny A, Morawin B, Ryterska K, Szczuko M.   +5 more
europepmc   +1 more source

Interleukin-1β in circulating mononuclear cells predicts steatotic liver disease improvement after weight loss in subjects with obesity and prediabetes or type 2 diabetes. [PDF]

Cardiovasc Diabetol
Simeone PG, Costantino S, Liani R, Tripaldi R, Di Castelnuovo A, Tartaro A, Mengozzi A, Cosentino F, Cipollone F, Consoli A, Paneni F, Santilli F.   +11 more
europepmc   +1 more source

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Interleukin-1β Inhibits Glutamate Release in Hippocampus of Young, But Not Aged, Rats

Neurobiology of Aging, 1997
The proinflammatory cytokine, interleukin-1, is synthesized in neuronal and glial cells and is released in response to stress/injury. IL-1 exerts profound effects on the central nervous system, which include an inhibitory effect on synaptic activity in hippocampus, a brain area expressing a high density of IL-1 receptors.
C A, Murray, B, McGahon, S, McBennett, M A, Lynch   +3 more
openaire   +2 more sources

Neuronal DNA damage correlates with overexpression of interleukin-1β converting enzyme in APPV717F mice

Neurobiology of Aging, 2001
Transgenic APPV717F mice, homozygous for a human minigene encoding the V717F familial Alzheimer's disease mutation, develop Abeta plaques similar to those seen in Alzheimer patients and show evidence of neuronal cell drop out in CA2-3 regions of the hippocampus at 8 months of age and older. Interleukin-1 (IL-1)beta (IL-1beta) converting enzyme (ICE) is
J G, Sheng, R E, Mrak, R A, Jones, M M, Brewer, X Q, Zhou, J, McGinness, S, Woodward, K, Bales, S M, Paul, B, Cordell, W S, Griffin   +10 more
openaire   +2 more sources

Exposure to alcohol in utero blunts splenic sympathetic neural response to endotoxin and interleukin-1β in the rat

Journal of Neuroimmunology, 1997
Systemic administration of endotoxin (LPS) or interleukin-1beta (IL-1) to prepubertal rats induced a marked increase in splenic but not cardiac norepinephrine (NE) turnover, an index of sympathetic neural activity. In contrast, the splenic neural response was blunted in their fetal alcohol-exposed (FAE) cohorts.
Z, Gottesfeld, S, Simpson, M, Maier
openaire   +2 more sources

Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1β?

Progress in Neurobiology, 1998
Ageing is associated with impairments in a variety of biological functions, one of the most striking might be considered to be the impairment in cognitive function. This impairment probably relates to the vulnerability of the hippocampus to the ageing process, since several cognitive functions rely on the integrity of this brain area.
openaire   +2 more sources

PERBEDAAN KADAR INTERLEUKIN 1β ANTARA PERSALINAN PRETERM DAN KEHAMILAN NORMAL

Jurnal Doppler, 2019
Masalah utama pada persalinan preterm adalah terkait morbiditas dan mortalitas yang ditimbulkan, terutama dikarenakan sistem pernapasan yang imatur pada bayi yang lahir sebelum usia kehamilan 34 minggu. Hasil Riset Kesehatan Dasar tahun 2007 menunjukkan bahwa 78,5% dari kematian neonatal terjadi pada umur 0-6 hari dengan penyebab kematian adalah; 1 ...
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Δ9-Tetrahydrocannabinol Inhibits Transforming Growth Factor Î'1 Induced Pro-Fibrotic and Nociceptive Gene Expression and Stimulates Interleukin 1Î' MRNA Expression in Human Intestinal Myofibroblasts

Gastroenterology, 2017
Christopher Broxson, Ellen M. Zimmermann
openaire   +1 more source