Results 121 to 130 of about 814,199 (330)
Endothelin‐1 induces expression of fetal genes through the interleukin‐6 family of cytokines in cardiac myocytes [PDF]
, 1999 Shuichi Saito +5 more
openalex +1 more source
Arthritis Care &Research, Accepted Article.Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist [PDF]
Proceedings of the Nutrition Society, 1994 N. Joseph Espat +3 more
openaire +1 more source
Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. [PDF]
, 2019 BackgroundThe mechanisms whereby neuroinflammation negatively affects neuronal function in the hypothalamus are not clear. Our previous study determined that obesity-mediated chronic inflammation elicits sex-specific impairment in reproductive function ...
Coss, Djurdjica, Lainez, Nancy M
core +1 more source
Sex differences in medication discontinuation in axial spondyloarthritis.
Arthritis Care &Research, Accepted Article.Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or Janus kinase inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we ...
Rachael Stovall +9 more
wiley +1 more source
Efficacy of Interleukin-1β Inhibitor on Dry Eye Disease in Patients with Degenerative Arthritis
Clinical Ophthalmology, 2023 Nathapon Treewipanon,1 Ngamjit Kasetsuwan,1,2 Usanee Reinprayoon,1,2 Vannarut Satitpitakul,1,2 Lita Uthaithammarat,1 Thanathep Tanpowpong3 1Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial ...
Treewipanon N +5 more
doaj
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Analysis of the salivary levels of immune biomarkers after inhalation of a steam mixed gas containing hydrogen gas [PDF]
, 2017 スイソニアから発生する水素ガス（濃度0.1～0.3％）を含む蒸気混合ガス“XEN”を鼻カニューラで吸入した。吸入後、唾液中の免疫バイオマーカーの動態を酵素抗体法（enzyme immunoassay：EIA）で解析した。その結果、“XEN”吸入15分後、唾液中のインターロイキン-1β（IL-1β）の濃度が吸入前と比較して有意に増加した ...
Nobunao IKEWAKI +4 more
core
Advanced Functional Materials, EarlyView.This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley +1 more source
Advanced Functional Materials, EarlyView.A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria +7 more
wiley +1 more source