Results 261 to 270 of about 24,572,041 (402)

Effects of interleukin-1 receptor antagonism in women with polycystic ovary syndrome-the FertIL trial. [PDF]

open access: yesFront Endocrinol (Lausanne)
Wälchli-Popovic M   +11 more
europepmc   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

open access: yesAdvanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu   +7 more
wiley   +1 more source

Interleukin-1 Inhibition for the Prevention and Treatment of Heart Failure. [PDF]

open access: yesJ Cardiovasc Pharmacol
Jafree E   +8 more
europepmc   +1 more source

25-Hydroxycholesterol suppresses interleukin-1–driven inflammation downstream of type I interferon

open access: yesScience, 2014
A. Reboldi   +5 more
semanticscholar   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

open access: yesAdvanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin   +7 more
wiley   +1 more source

Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles. [PDF]

open access: yesElife
Zheng X   +15 more
europepmc   +1 more source

Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion

open access: yesAdvanced Science, EarlyView.
This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng   +13 more
wiley   +1 more source

Interleukin-1 signaling and CD4<sup>+</sup> T cells control B cell recruitment to the lungs in chronic beryllium disease. [PDF]

open access: yesFront Immunol
Gaballa JM   +10 more
europepmc   +1 more source

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