Results 81 to 90 of about 10,723,036 (376)
Hyporesponsiveness to the anti-inflammatory action of interleukin-10 in type 2 diabetes
Scientific Reports, 2016 Chronic low-grade inflammation contributes to the pathology and complications of type 2 diabetes (T2D). Interleukin-10 (IL10), an anti-inflammatory cytokine, is suggested to play a protective role in T2D.
J. Barry +7 more
semanticscholar +1 more source
Hubungan Peningkatan Interleukin-10 Akibat Infestasi Cacing Usus Nematoda terhadap Spektrum Morbus Hansen [PDF]
, 2015 Morbus Hansen (MH) adalah infeksi kronis yang disebabkan oleh Mycobacterium leprae, yang mengenai saraf perifer, kulit, dan organ lain kecuali susunan saraf pusat. Pertahanan terhadap M.
Lukas, R. (Rika) +3 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Journal of Infection in Developing Countries, 2019 Introduction: Immune response to genital Chlamydia trachomatis infection is involved in both immunity and pathology. The cytokine profile during infection has been implicated in the disease outcome, either resolution or severe sequelae.
Alessandra Bua +3 more
doaj +1 more source
Journal of Experimental Medicine, 1999 A T helper cell type 1–mediated colitis develops in severe combined immunodeficient mice after transfer of CD45RBhigh CD4+ T cells and can be prevented by cotransfer of the CD45RBlow subset.
C. Asseman +4 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Interleukin-10 Family and Tuberculosis: An Old Story Renewed
International Journal on Biological Sciences, 2016 The interleukin-10 (IL-10) family of cytokines consists of six immune mediators, namely IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. IL-10, IL-22, IL-24 and IL-26 are critical for the regulation of host defense against Mycobacterium tuberculosis ...
A. E. Abdalla +3 more
semanticscholar +1 more source
Interleukin-12B & interleukin-10 gene polymorphisms in pulmonary tuberculosis [PDF]
, 2007 Background & objectives: Cytokines play an important role in anti-tuberculosis immune response. Skewing of immunity from protective to pathogenic may involve a shift in Th1-Th2 paradigm.
Ashilakshmi, A R +4 more
core
Comparison of LPS-stimulated release of cytokines in punch versus transwell tissue culture systems of human gestational membranes [PDF]
, 2010 Background Cytokine signaling within the amnionic, chorionic and decidual extraplacental gestational membranes plays an important role in membrane rupture and the timing of birth.
Loch-Caruso, Rita, Miller, Mark F.
core +4 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source