Results 1 to 10 of about 973,470 (302)

Adropin and spexin hormones regulate the systemic inflammation in adenine-induced chronic kidney failure in rat

Chinese Journal of Physiology, 2021
Chronic kidney disease is one of the major global health problems. Chronic renal failure is stimulated by many cytokines and chemokines. Adropin and spexin (SPX) are peptides hormones.
Gulsun Memi, Burak Yazgan
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Partial purification and functional characterization of Ts19 Frag-I, a novel toxin from Tityus serrulatus scorpion venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background The yellow scorpion Tityus serrulatus (Ts) is responsible for the highest number of accidents and the most severe scorpion envenoming in Brazil. Although its venom has been studied since the 1950s, it presents a number of orphan peptides that
Priscila C. Lima, Karla C. F. Bordon, Manuela B. Pucca, Felipe A. Cerni, Karina F. Zoccal, Lucia H. Faccioli, Eliane C. Arantes   +6 more
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The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature

Frontiers in Immunology, 2021
The level of immunoglobulins and cytokines changes with an ageing immune system. This review summarizes findings from studies that have examined the impact of acute and chronic exercise on immunoglobulins and cytokines in the elderly.
Maha Sellami, Nicola Luigi Bragazzi, Nicola Luigi Bragazzi, Baha Aboghaba, Mohamed A. Elrayess   +4 more
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Keratin-Butyrate Scaffolds Promote Skin Wound Healing in Diabetic Rats Through Down-Regulation of IL-1β and Up-Regulation of Keratins 16 and 17

Journal of Natural Fibers, 2023
Impaired wound healing particularly in diabetics creates a significant healthcare burden. The study aimed to evaluate the effect of keratin-butyrate fibers (FKDP +0.1%NaBu) in a full-thickness skin wound model in 30 diabetic rats.
Marek Konop, Mateusz Rybka, Mateusz Szudzik, Łukasz Mazurek, Anna K. Laskowska, Dorota Sulejczak, Zbigniew Ruszczak, Rafał Mazgaj, Bartłomiej Cieślik, Robert A. Schwartz, Emilia Samborowska, Jakub Frankowski, Adam Waszkowski, Piotr Konopelski, Joanna Czuwara   +14 more
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Crossroad between the Heat Shock Protein and Inflammation Pathway in Acquiring Drug Resistance: A Possible Target for Future Cancer Therapeutics

Biomedicines, 2023
The development of multidrug resistance (MDR) against chemotherapeutic agents has become a major impediment in cancer therapy. Understanding the underlying mechanism behind MDR can guide future treatment for cancer with better therapeutic outcomes ...
Prathap Somu, Nagaraj Basavegowda, Levin Anbu Gomez, Hulikunte Veeranna Jayaprakash, Gangadahosahalli Krishnegowda Puneetha, Akhilesh Kumar Yadav, Subhankar Paul, Kwang-Hyun Baek   +7 more
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Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis

Molecules, 2021
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly symmetric, which causes joint inflammation, cartilage degeneration and bone erosion, resulting in deformity and the loss of physical function. Although the management of
Tapan Behl, Tanuj Upadhyay, Sukhbir Singh, Sridevi Chigurupati, Amal M. Alsubayiel, Vasudevan Mani, Celia Vargas-De-La-Cruz, Diana Uivarosan, Cristiana Bustea, Cristian Sava, Manuela Stoicescu, Andrei-Flavius Radu, Simona Gabriela Bungau   +12 more
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The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications

Cells, 2021
Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 and IL-33) and Th17 (IL-17, IL-17F, IL-21, IL-22, IL-23 and TGF-
Anna Waśkiel-Burnat, Marta Osińska, Anna Salińska, Leszek Blicharz, Mohamad Goldust, Małgorzata Olszewska, Lidia Rudnicka   +6 more
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Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

Endocrine Connections, 2020
Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient i ncreases in cortisol and ACTH secretion occurred.
Ferdinand Roelfsema, Peter Y Liu, Rebecca Yang, Paul Takahashi, Johannes D Veldhuis   +4 more
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Emerging Roles of Dysregulated MicroRNAs in Myasthenia Gravis

Frontiers in Neuroscience, 2020
Myasthenia gravis (MG) is a rare acquired autoimmune neuromuscular disease. Autoantibodies, cellular immunity, complement, and cytokines are involved in the pathogenesis of MG. It is characterized by the dysfunction of neuromuscular junction transmission
Lin Wang, Lijuan Zhang
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Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

Pharmaceuticals, 2022
Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation of ...
Ajjampura C. Vinayaka, Nurit Shalev, Seegehalli M. Anil, Sudeep Tiwari, Navin Kumar, Eduard Belausov, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai   +8 more
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