Results 31 to 40 of about 1,003,113 (304)

Interleukin-18 [PDF]

open access: yes, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B.   +2 more
core   +1 more source

Crossroad between the Heat Shock Protein and Inflammation Pathway in Acquiring Drug Resistance: A Possible Target for Future Cancer Therapeutics

open access: yesBiomedicines, 2023
The development of multidrug resistance (MDR) against chemotherapeutic agents has become a major impediment in cancer therapy. Understanding the underlying mechanism behind MDR can guide future treatment for cancer with better therapeutic outcomes ...
Prathap Somu   +7 more
doaj   +1 more source

Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis

open access: yesMolecules, 2021
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly symmetric, which causes joint inflammation, cartilage degeneration and bone erosion, resulting in deformity and the loss of physical function. Although the management of
Tapan Behl   +12 more
doaj   +1 more source

The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications

open access: yesCells, 2021
Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 and IL-33) and Th17 (IL-17, IL-17F, IL-21, IL-22, IL-23 and TGF-
Anna Waśkiel-Burnat   +6 more
doaj   +1 more source

Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

open access: yesEndocrine Connections, 2020
Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient i ncreases in cortisol and ACTH secretion occurred.
Ferdinand Roelfsema   +4 more
doaj   +1 more source

cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]

open access: yes, 2000
By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter   +15 more
core   +1 more source

Emerging Roles of Dysregulated MicroRNAs in Myasthenia Gravis

open access: yesFrontiers in Neuroscience, 2020
Myasthenia gravis (MG) is a rare acquired autoimmune neuromuscular disease. Autoantibodies, cellular immunity, complement, and cytokines are involved in the pathogenesis of MG. It is characterized by the dysfunction of neuromuscular junction transmission
Lin Wang, Lijuan Zhang
doaj   +1 more source

Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

open access: yesPharmaceuticals, 2022
Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation of ...
Ajjampura C. Vinayaka   +8 more
doaj   +1 more source

Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti-inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages [PDF]

open access: yesJournal of HerbMed Pharmacology, 2022
Introduction: Antidesma thwaitesianum Müll. Arg is a tropical fruit, which has been commonly used for healthy food and traditional herbal medicine. This study aimed to investigate the anti-inflammatory effects of A. thwaitesianum fruit extract (AFE) rich
Orapin Insuan   +5 more
doaj   +1 more source

Mathematical modeling of interleukin-27 induction of anti-tumor T cells response. [PDF]

open access: yes, 2014
Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon-[Formula: see text] secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer treatment.
Kang-Ling Liao, Xue-Feng Bai, and Avner Friedman   +9 more
core   +1 more source

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