Results 151 to 160 of about 3,870,583 (322)

Lebrikizumab Rapidly Lowers Inflammatory Biomarkers with Clinical Correlations in Moderate-to-Severe Atopic Dermatitis

Dermatology and Therapy
Introduction Lebrikizumab is a novel monoclonal antibody that selectively binds to interleukin (IL)-13 with high affinity and a slow dissociation rate.
Emma Guttman-Yassky, Zhe Sun, Laura Rebeca Mena, Nathan Hahn, Brian J. Nickoloff, Christoph Preuss, Kimberly Siu, Chitra R. Natalie, Gaia Gallo, Eric Wolf, Kilian Eyerich, Mònica Aparici, Robert J. Benschop, Angela Okragly   +13 more
doaj   +1 more source

Distinct Structural Requirements for Interleukin-4 (IL-4) and IL-13 Binding to the Shared IL-13 Receptor Facilitate Cellular Tuning of Cytokine Responsiveness [PDF]

, 2009
Takachika Ito, Shoichi Suzuki, Sachiko Kanaji, Hiroshi Shiraishi, Shoichiro Ohta, Kazuhiko Arima, Go Tanaka, Taro Tamada, Eijiro Honjo, K. Christopher García, Ryota Kuroki, Kenji Izuhara   +11 more
openalex   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants

, 2019
Andrea Stadnikova, Peter Trošan, Pavlína Skalická, Tor Paaske Utheim, Kateřina Jirsová   +4 more
openalex   +2 more sources

From Macrophage Interleukin-13 Receptor to Foam Cell Formation [PDF]

, 2012
Valentin P. Yakubenko, Linda C. Hsi, Martha K. Cathcart, Ashish Bhattacharjee   +3 more
openalex   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Administration of mesenchymal stem cell derivate secretome causes lower levels of Matrix Metalloproteinase-13, Aggrecanase-2, and Interleukin-1β than hyaluronic acid in rabbit knee osteoarthritis

, 2023
Cokorda Gde Oka Dharmayuda, I Ketut Siki Kawiyana, I Made Bakta, I Nyoman Mantik Astawa, Putu Astawa, Ida Bagus Putra Manuaba, I Ketut Suyasa, Anak Agung Ngurah Subawa, Heri Suroto, Luh Putu Lin Indrayani Maker   +9 more
openalex   +2 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Expression, charakterization and biological functions of interleukin-4/interleukin-13 receptor complexes in different cell types

, 1997
Ningping Feng
openalex   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source