Results 211 to 220 of about 419,343 (249)
Some of the next articles are maybe not open access.
European Journal of Cancer, 2014
Material and Methods: To evaluate the extent of ITH in colorectal cancer (CRC) with microsatellite instability (MSI), we obtained 4−7 biopsies from 39 CRCs followed by MSI analysis either using the Bethesda MSI evaluation system or Promega system with 5 mononucleotide markers.
Y. Eun, H. Chung, Y.C. Lee
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Material and Methods: To evaluate the extent of ITH in colorectal cancer (CRC) with microsatellite instability (MSI), we obtained 4−7 biopsies from 39 CRCs followed by MSI analysis either using the Bethesda MSI evaluation system or Promega system with 5 mononucleotide markers.
Y. Eun, H. Chung, Y.C. Lee
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Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors
2019The IL-17 family in humans consists of six distinct cytokines (IL-17A-F) that can interact with five IL-17 receptors (IL-17RA-E). The interaction between these cytokines and their receptors are critical in mediating host defenses while also making major contributions to inflammatory and autoimmune responses as demonstrated through both in vitro and in ...
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Journal of Investigative Medicine, 2006
Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
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Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
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An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling
Protein & Peptide Letters, 2015Interleukin-17A (IL-17A) and its receptor (IL-17RA) are prototype members of IL-17 ligand/receptor family firstly identified in CD4+ T cells, which comprises six ligands (IL-17A to IL- 17F) and five receptors (IL-17RA to IL-17RE). IL-17A is predominantly secreted by T helper 17 (Th17) cells, and plays important roles in the development of autoimmune ...
Krstić, Jelena +6 more
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Functional characterization of interleukin 17 family members and their receptors in amphioxus
International Journal of Biological MacromoleculesThe interleukin 17 (IL17) cytokine family plays a crucial role in phylogenetically conserved immune defense mechanisms, broadly categorized into two distinct evolutionary lineages: the invertebrate-derived (i-type) and vertebrate-specific (v-type) IL17 homologs.
Haifeng, Li +7 more
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Critical Care Management of Chimeric Antigen Receptor T-Cell Therapy Recipients
Ca-A Cancer Journal for Clinicians, 2022Sandrine Valadè +2 more
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Interleukin-6 Receptor Antagonists in Critically Ill Patients With Covid-19
New England Journal of Medicine, 2021Patrick Lawler +2 more
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