Results 221 to 230 of about 128,073,262 (258)

The systemic administration of multipotent mesenchymal stromal cells alters the inflammatory response in the lung during murine polymicrobial sepsis. [PDF]

Cell Tissue Res
Kanewska A, Lackner I, Dechant M, Friedrich A, Herrmann M, Rojewski M, Perl M, Preßmar J, Schrezenmeier H, Kalbitz M.   +9 more
europepmc   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Blocking IL-6 trans-signaling mitigates benzalkonium chloride-induced inflammation, oxidative imbalance, ER stress, and barrier disruption in human corneal epithelial cells. [PDF]

Eye Vis (Lond)
Lax K, Glass J, Aliste A, Sharma A, Sharma S.   +4 more
europepmc   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Immunometabolic regulation of cardiac macrophages in heart failure with preserved ejection fraction. [PDF]

Front Immunol
Liang J, Su M, Liu R, Li T, Qin Z, Wang Y.   +5 more
europepmc   +1 more source

Unveiling the therapeutic mechanisms of Eucommia ulmoides-Achyranthes bidentata in osteoporosis: A network pharmacology and molecular docking study. [PDF]

Medicine (Baltimore)
Li K, Jia Y, Cai T, Chong H, Shen Y, Sun J.   +5 more
europepmc   +1 more source

Resting and postprandial inflammasome and metabolic biomarkers in chronic spinal cord injury. [PDF]

Spinal Cord Ser Cases
Dusseau NB, Farkas GJ, Nash MS, Brenman JS, Keane RW, Dietrich WD, Levi AD, de Rivero Vaccari JP, McMillan DW.   +8 more
europepmc   +1 more source