Results 131 to 140 of about 23,391 (181)

Evolution of interleukin-1β

Cytokine & Growth Factor Reviews, 2002
All jawed vertebrates possess a complex immune system, which is capable of anticipatory and innate immune responses. Jawless vertebrates possess an equally complex immune system but with no evidence of an anticipatory immune response. From these findings it has been speculated that the initiation and regulation of the immune system within vertebrates ...
Steve, Bird, Jun, Zou, Tiehui, Wang, Barry, Munday, Charlie, Cunningham, Chris J, Secombes   +5 more
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The Presence of Interleukin-1beta in the Bovine Reproductive Tract

Journal of Interferon & Cytokine Research, 1999
Interleukin-1 (IL-1) is a pleiotropic cytokine implicated in endometrial and embryonic physiology. Our objective was to determine the presence of IL-1 in the endometrium, oviduct, and uterine fluid of cows at days 0, 7, and 14 of the estrous cycle. Immunoreactive IL-1beta was identified in endometrial and oviductal tissues throughout the estrous cycle ...
F F, Paula-Lopes, A A, de Moraes, P J, Hansen   +2 more
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Biological activity of human epidermal interleukin-1beta: comparison with recombinant human interleukin-1beta.

European cytokine network, 1998
We have recently presented evidence that human plantar stratum corneum and psoriatic scales contain biologically active interleukin-1beta (IL-1beta) which has been activated in a process not involving interleukin-1beta-converting-enzyme. The aim of the present study was to compare this form of native IL-1beta with recombinant mature human IL-1beta as ...
Nylander Lundqvist, E, Companjen, AR (Arjen), Prens, Errol, Egelrud, T   +3 more
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[Interleukin-1beta and depressive states].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002
Administration of Interleukin-1 beta (IL-1 beta) in pyrogenic and subpyrogenic doses induced a depression of social and exploratory behaviour in rats. A reduction in locomotor activity only occurred with pyrogenic doses of the IL-1 beta. The low dose induced the reduction whereas the high dose the increase of anxiety in elevated plus maze. The opposite
O E, Zubareva, O M, Efremov, A S, Simbirtsev, V M, Klimenko   +3 more
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Caspase‐1/interleukin‐1beta signaling in diabetic retinopathy

Acta Ophthalmologica, 2008
Abstract Purpose The pro‐inflammatory cytokine, interleukin‐1β (IL‐1β), is known to induce vascular dysfunction and cell death. Previously, we have shown that caspase‐1 activity is increased in retinas of diabetic and galactosemic mice, and diabetic patients.
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Interleukin-1beta (IL-1beta) processing pathway.

Science signaling, 2010
The innate immune system senses molecular patterns from invading microorganisms. Once activated, it orchestrates the inflammatory response by secreting proinflammatory cytokines, such as interleukin-1 (IL-1)-type cytokines, in particular IL-1beta. IL-1 mediates the expression of a vast array of genes involved in secondary inflammation.
Axel, Weber, Peter, Wasiliew, Michael, Kracht   +2 more
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Interleukin-1beta gene in esophageal, gastric and colorectal carcinomas.

Oncology reports, 2007
Interleukin (IL)-1 gene polymorphisms are associated with development of gastric atrophy and with increased risk of gastric carcinoma. A -31C to T base transition in the promoter region of this gene is involved in carcinogenic changes within the stomach, especially in Helicobacter pylori infected individuals.
H, Ito, K, Kaneko, R, Makino, K, Konishi, T, Kurahashi, T, Yamamoto, A, Katagiri, Y, Kumekawa, Y, Kubota, T, Muramoto, K, Mitamura, M, Imawari   +11 more
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LL-Z1271alpha: an interleukin-1beta production inhibitor.

Biochemical and biophysical research communications, 2001
LL-Z1271alpha, a fungal metabolite, dose-dependently inhibited interleukin-1beta (IL-1beta) production in lipopolysaccharide (LPS)-stimulated human whole blood. Oral administration of LL-Z1271alpha to LPS-challenged mice caused significant lowering in the IL-1beta levels in peritoneal cavity.
K, Ichikawa, T, Inagaki, H, Kachi-Tonai, Y, Kojima, T, Nakamura , H, Nishida, Y, Ueno, P, Binding, C A, Gabel, V, Lucas, P A, McNiff, N, Kojima   +11 more
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Interleukin-1beta stimulates phospholipase A2 activity in adult rat ventricular myocytes

American Journal of Physiology-Cell Physiology, 1997
We have examined whether interleukin (IL)-1beta modulates phospholipase A2 (PLA2) activity in ventricular myocytes. PLA2 activity was measured in isolated membrane and cytosol fractions with (16:0,[3H]18:1) plasmenylcholine and (16:0,[3H]18:1) phosphatidylcholine in the absence and presence of Ca2+.
J, McHowat, S, Liu
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