Th17 and Interleukin 23 in the Pathogenesis of Psoriatic Arthritis and Spondyloarthritis [PDF]
Alberto Cauli, Alessandro Mathieu
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Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Studying the Serum as Well as Serous Level of IL-17 and IL-23 in Patients with Serous Otitis Media
Serous otitis media with effusion (OME) is a middle ear inflammatory response to allergens and microbes which stimulate leukocytes to produce different inflammatory mediators after obstruction of Eustachian tube. Here, we investigated the levels of these
Ahmad Yeghaneh Moghaddam +3 more
doaj
Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu +6 more
wiley +1 more source
The study of interleukin-23 and interleukin-10 serum levels in patients with rheumatoid arthritis compared to osteoporosis and healthy subjects [PDF]
زمینه و هدف: سیتوکین ها در روندهایی که باعث التهاب، تخریب مفصلی و علائم خارج مفصلی که به همراه آرتریت روماتوئید دیده می شود، دارای نقش اساسی هستند. هدف از این مطالعه، بررسی نقش اینترلوکین-23 و اینترلوکین-10 در بیماری آرتریت روماتوئید قبل از درمان و سه ...
Hossenian, Mahdieh. +2 more
core
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
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Assessment of T helper 17-associated cytokines in thromboangiitis obliterans
Shayan Keramat,1 Mohammad Hadi Sadeghian,1,2 Mohammad Reza Keramati,1,2 Bahare Fazeli3,4 1Hematology Department, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran; 2Pathology Department, Cancer Molecular Pathology ...
Keramat S +3 more
doaj
Tildrakizumab in the treatment of psoriasis: latest evidence and place in therapy. [PDF]
Psoriasis is a chronic inflammatory disorder that is clinically characterized by scaly cutaneous plaques. New evidence suggests that dysregulation of interleukin (IL)-23, a key cytokine in the T-helper-17 pathway, plays a vital role in the development of
Lee, Erica B +4 more
core
IL‐2 Free Expansion of T Cells with Immunofilaments
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source
Correction to: Critical role of interleukin-23 in development of asthma promoted by cigarette smoke [PDF]
Hyun Seung Lee +6 more
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