Results 111 to 120 of about 2,027,182 (132)
Evaluation of interleukin‐38 levels in serum of patients with coronavirus disease 2019 [PDF]
Journal of Medical Virology, 2022 Abstract Interleukin‐38 (IL‐38) has recently been considered as a cytokine with anti‐inflammatory properties in viral respiratory infections, particularly coronavirus disease 19 (COVID‐19), but the evidence has not been well elucidated.
Wasan W. Al‐bassam +3 more
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Interleukin-38 in colorectal cancer: a potential role in precision medicine [PDF]
Cancer Immunology, Immunotherapy, 2019 Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising sensitive/specific marker(s).
Feier Chen +5 more
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Plasma levels of interleukin-38 in healthy aging and in type 2 diabetes
Diabetes Research and Clinical Practice, 2021 Plasma levels of interleukin (IL)-38 were evaluated in patients with type 2 diabetes (T2DM) and healthy controls. Plasma IL-38 was higher in T2DM patients and positively related to waist/hip ratio, HbA1c, uric acid, liver function tests, triglycerides and total proteins. Patients suffering from diabetic nephropathy had the highest IL-38 levels.
Felicia, Gurău +6 more
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Interleukin-38 in atherosclerosis
Clinica Chimica Acta, 2022Chronic inflammation caused by immune cells and their mediators is a characteristic of atherosclerosis. Interleukin-38 (IL-38), a member of the IL-1 family, exerts multiple anti-inflammatory effects via specific ligand-receptor interactions. Upon recognizing a specific receptor, IL-38 restrains mitogen-activated protein kinase (MAPK), nuclear factor ...
Xiao-Hong Zhang +3 more
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Biology of interleukin-38 and its role in chronic inflammatory diseases
International Immunopharmacology, 2021Interleukin (IL)-38 is the tenth member of the IL-1 cytokine family. IL-38 shares high similarity with IL-36Ra and IL-1Ra and can bind to their receptors, thus exerting an anti-inflammatory effect. Despite the lack of a signal peptide, IL-38 can be released from several cell types, but its maturation process remains obscure.
Hua-song Xia +4 more
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Plasma interleukin-38 in patients with rheumatoid arthritis
International Immunopharmacology, 2018Previous studies have indicated that interleukin-38 (IL-38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL-38 in RA and discuss the potential of IL-38 as a biomarker for RA. Protein concentrations of IL-38 were examined by enzyme-linked immunosorbent assay, and the mRNA level of IL-38 was tested by ...
Wang-Dong, Xu +3 more
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Investigation of Interleukin-38 in patients with primary Sjögren’s Syndrome
Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, 2022Aim: Interleukin-38 has been involved as an inflammatory mediator in rheumatic diseases. However, little is known about the role of IL-38 in the development of primary Sjögren’s syndrome. The present study aimed to evaluate the role of IL-38 in primary Sjögren’s syndrome and its clinical relevance.
Selcan GÜLTUNA +2 more
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The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization
Current Molecular Medicine, 2019Background: Angiogenesis is tightly linked to inflammation. Cytokines of interleukin 1 (IL-1) family are key mediators in modulating inflammatory responses. Methods: In this study, we examined the role of IL-38, a member of the IL-1 family, in mediating inflammation-induced angiogenesis.
Jiangli, Zhu +8 more
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Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility
Immunology Letters, 2023Interleukin (IL)-38 and IL-41 are novel cytokines, but their role in male infertility (MI) is unknown. The purpose of this study was to measure the levels of serum IL-38 and IL-41 in patients with MI and correlate these levels with semen indexes.Eighty-two patients with MI and 45 healthy controls (HC) were recruited for this study.
Chunhao, Rong +4 more
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