Results 121 to 130 of about 1,897,702 (279)
Advanced Healthcare Materials, EarlyView.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source
Characterisation of the role of the IL-36 family of cytokines in the pathogenesis of colon cancer [PDF]
, 2022 The IL-36 cytokines are a recently described subset of the IL-1 family of cytokines. These cytokines have now been identified to play a role in the pathogenesis of many inflammatory diseases and are increasingly being implicated in tumourigenesis ...
Baker, Kevin J.
core
Advanced Healthcare Materials, EarlyView.A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Impact of chronic hyperglycaemia on the coronary microcirculation - benefits of targeting IL-36 and diet reversal [PDF]
Following myocardial infarction (MI), patients with type 2 diabetes mellitus (T2DM) have poorer prognosis which may be linked to increased susceptibility of coronary microvessels to injury.
Cleary, Simon +6 more
core +4 more sources
The differential role of IL-33 and IL-38 in prostate cancer, contradictory roles [PDF]
Prostate cancer (PCa) is still as a major cause of morbidity and mortality in men at the global level, highlighting the necessity for improved diagnostic and therapeutic strategies beyond current PSA screening limitations. This mini-review focuses on the
Bin Zhou +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad +2 more
wiley +1 more source
Role of IL-38 and Its Related Cytokines in Inflammation
Mediators of Inflammation, 2015 Interleukin- (IL-) 38 is a recently discovered cytokine and is the tenth member of the IL-1 cytokine family. IL-38 shares structural features with IL-1 receptor antagonist (IL-1Ra) and IL-36Ra. IL-36R is the specific receptor of IL-38, a partial receptor
Xianli Yuan +3 more
doaj +1 more source
GC-MS and Molecular Docking Analyses of Phytoconstituents from the Plant Tephrosia purpurea [PDF]
Introduction: Medicinal plants are extremely useful assets in the development of novel medications and plant-derived treatments. The use of herbs in the treatment of chronic and acute diseases, as well as a wide range of ailments and issues, including ...
Smrutiranjan Dash, Naimish Nanda, Mrutyunjay Bhanja, Rupali Bharti Sao, Ayushmaan Roy, Reema Dash
core +1 more source
Correlation of peripheral blood ZO⁃1 and IL⁃38 levels with lung injury degree in patients with acute respiratory distress syndrome [PDF]
Objective To analyze the changes of zonula occludens⁃1（ZO⁃1）and interleukin⁃38（IL⁃38）levels in peripheral blood of acute respiratory distress syndrome（ARDS）patients with different degrees of lung injury，and their correlations with the degree of lung ...
HE Yanxia，XUE Bing，WU Wenjie，CHEN Xing
core +2 more sources
Advanced Materials, EarlyView.An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang +5 more
wiley +1 more source