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Interleukin-38 and Insulin Resistance
Endocrine, Metabolic & Immune Disorders - Drug TargetsAbstract: Insulin resistance, i.e., decreased biological response to insulin, is a risk factor for many diseases, such as obesity, type 2 diabetes (T2DM), cardiovascular disease, polycystic ovary syndrome, some forms of cancer and neurodegenerative diseases.
Kamil Klejbuk, Marek Strączkowski
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Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis
Naunyn-Schmiedeberg's Archives of Pharmacology, 2020Pulmonary fibrosis is a kind of pulmonary disorder with chronic inflammation and excessive collagen deposition, and its etiology is not clear. Interleukin (IL)-38 is a new member of IL-1 family cytokines, but its role in pulmonary fibrosis has not been elucidated.
Zhiwei Xu +4 more
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Correlation of Rheumatoid Arthritis with Interleukin-38 and its Polymorphism (rs6743376)
Scandic Journal Of Advanced Research And Reviews, 2023Among autoimmune disorders, rheumatoid arthritis is one of the most prevalent. The IL-1 family and the IL36 subfamily both include interleukin-38. IL-38 is anti-inflammatory cytokine. IL-38 is essential for inflammation control and host defense. In the Pakistani population, this research intends to evaluate the relationship flanked by IL-38 levels and ...
Mohammed Issa Ibrahim Islemeh +2 more
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Serum levels of interleukin-38 in sufferers with atopic eczema
Egyptian Journal of Dermatology and Venerology, 2019Background The relation between interleukin-38 (IL-38) and atopy is not precisely regarded yet. The current study has a look at set to assess the serum level of IL-38 in atopy patients and controls in order to illustrate the disease association and correlation with severity.
FathiaM Khattab +2 more
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Interleukin-38 increases the insulin sensitivity in children with the type 2 diabetes
International Immunopharmacology, 2020The prevalence of type 2 diabetes mellitus (DM) is increasing in the children population. It is well known that inflammation contributes to the type 2 DM pathogenesis. Interleukin 38 (IL-38) is one newly identified anti-inflammatory factor. Therefore, we investigated whether the expression level of IL-38 is associated with type 2 DM in the children and
Ying, Liu +4 more
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International Ophthalmology, 2023
The objective of the study was to analyse the levels of IL-17 and IL-38 in the samples of unstimulated tears, orbital adipose tissues, and sera of patients diagnosed with active forms of TAO. The correlation of the levels of IL-17 and IL-38 with clinical activity score (CAS) was scrutinized.A study was conducted at the Kazakhstan Scientific Research ...
Ainura, Mussakulova +8 more
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The objective of the study was to analyse the levels of IL-17 and IL-38 in the samples of unstimulated tears, orbital adipose tissues, and sera of patients diagnosed with active forms of TAO. The correlation of the levels of IL-17 and IL-38 with clinical activity score (CAS) was scrutinized.A study was conducted at the Kazakhstan Scientific Research ...
Ainura, Mussakulova +8 more
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Interleukin-38 is elevated in inflammatory bowel diseases and suppresses intestinal inflammation
Cytokine, 2020There has been no report investigating the role of IL-38 in inflammatory bowel diseases (IBD). Therefore, we investigated the expression of IL-38 in IBD patients and its role in regulating intestinal inflammation. The levels of IL-38 were significantly elevated in the intestine of IBD patients and DSS-induced colitis mice.
Cheng, Xie +6 more
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Decision letter for "Interleukin‐38: A crucial player in periodontitis"
2023openaire +2 more sources