Results 171 to 180 of about 1,628,367 (268)
Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion
This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng+13 more
wiley +1 more source
Negative Correlation of Interleukin-38 Serum Level with Alkaline Phosphatase and Persistent Hepatitis C Infection [PDF]
Najmeh Rokhtabnak+7 more
openalex +1 more source
Association of Resistin & Interleukin 6 in Ischemic Heart Disease and Diabetic Patients
Background: Honey is used extensively in south East Asia, Middle and Far Eastern countries as a sweetener as well as medication for its anti-bacterial, anti-fungal, and anti-viral properties with no risk of resistance or side effects.
Faisal Yaseen
doaj
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao+17 more
wiley +1 more source
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang+8 more
wiley +1 more source
PDB - 5FB8: Structure of Interleukin-16 bound to the mAb 14.1 (311K, 38°C, 200 ns) - random seed #5
Razvan Stan
openalex +2 more sources
This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng+27 more
wiley +1 more source
Expression of concern: Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression. [PDF]
Wang F, Zhang W, Wu T, Chu H.
europepmc +1 more source
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan+6 more
wiley +1 more source