Results 201 to 210 of about 393,705 (229)

Evaluation of interleukin‐38 levels in serum of patients with coronavirus disease 2019 [PDF]

open access: yesJournal of Medical Virology, 2022
AbstractInterleukin‐38 (IL‐38) has recently been considered as a cytokine with anti‐inflammatory properties in viral respiratory infections, particularly coronavirus disease 19 (COVID‐19), but the evidence has not been well elucidated. Therefore, a case‐control study was conducted to determine IL‐38 serum levels in 148 patients with COVID‐19 (45 ...
Wasan W. Al‐bassam   +3 more
openaire   +3 more sources

Interleukin-38 in colorectal cancer: a potential role in precision medicine [PDF]

open access: yesCancer Immunology, Immunotherapy, 2019
Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising sensitive/specific marker(s).
Feier Chen   +5 more
openaire   +3 more sources
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Interleukin-38 in atherosclerosis

Clinica Chimica Acta, 2022
Chronic inflammation caused by immune cells and their mediators is a characteristic of atherosclerosis. Interleukin-38 (IL-38), a member of the IL-1 family, exerts multiple anti-inflammatory effects via specific ligand-receptor interactions. Upon recognizing a specific receptor, IL-38 restrains mitogen-activated protein kinase (MAPK), nuclear factor ...
Xiao-Hong Zhang   +3 more
openaire   +2 more sources

Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020
Pulmonary fibrosis is a kind of pulmonary disorder with chronic inflammation and excessive collagen deposition, and its etiology is not clear. Interleukin (IL)-38 is a new member of IL-1 family cytokines, but its role in pulmonary fibrosis has not been elucidated.
Zhiwei Xu   +4 more
openaire   +2 more sources

Biology of interleukin-38 and its role in chronic inflammatory diseases

International Immunopharmacology, 2021
Interleukin (IL)-38 is the tenth member of the IL-1 cytokine family. IL-38 shares high similarity with IL-36Ra and IL-1Ra and can bind to their receptors, thus exerting an anti-inflammatory effect. Despite the lack of a signal peptide, IL-38 can be released from several cell types, but its maturation process remains obscure.
Hua-song Xia   +4 more
openaire   +2 more sources

Plasma interleukin-38 in patients with rheumatoid arthritis

International Immunopharmacology, 2018
Previous studies have indicated that interleukin-38 (IL-38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL-38 in RA and discuss the potential of IL-38 as a biomarker for RA. Protein concentrations of IL-38 were examined by enzyme-linked immunosorbent assay, and the mRNA level of IL-38 was tested by ...
Wang-Dong, Xu   +3 more
openaire   +2 more sources

Investigation of Interleukin-38 in patients with primary Sjögren’s Syndrome

Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, 2022
Aim: Interleukin-38 has been involved as an inflammatory mediator in rheumatic diseases. However, little is known about the role of IL-38 in the development of primary Sjögren’s syndrome. The present study aimed to evaluate the role of IL-38 in primary Sjögren’s syndrome and its clinical relevance.
Selcan GÜLTUNA   +2 more
openaire   +1 more source

Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility

Immunology Letters, 2023
Interleukin (IL)-38 and IL-41 are novel cytokines, but their role in male infertility (MI) is unknown. The purpose of this study was to measure the levels of serum IL-38 and IL-41 in patients with MI and correlate these levels with semen indexes.Eighty-two patients with MI and 45 healthy controls (HC) were recruited for this study.
Chunhao, Rong   +4 more
openaire   +2 more sources

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