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Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility.
Immunology Letters, 2023BACKGROUND Interleukin (IL)-38 and IL-41 are novel cytokines, but their role in male infertility (MI) is unknown. The purpose of this study was to measure the levels of serum IL-38 and IL-41 in patients with MI and correlate these levels with semen ...
Chunhao Rong +4 more
semanticscholar +3 more sources
Biology of interleukin-38 and its role in chronic inflammatory diseases.
International Immunopharmacology, 2021Interleukin (IL)-38 is the tenth member of the IL-1 cytokine family. IL-38 shares high similarity with IL-36Ra and IL-1Ra and can bind to their receptors, thus exerting an anti-inflammatory effect.
Hua-song Xia +4 more
semanticscholar +3 more sources
Plasma interleukin‐38 in patients with rheumatoid arthritis
International Immunopharmacology, 2018&NA; Previous studies have indicated that interleukin‐38 (IL‐38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL‐38 in RA and discuss the potential of IL‐38 as a biomarker for RA.
Wang-Dong Xu +3 more
semanticscholar +3 more sources
Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis
Naunyn-Schmiedeberg's Archives of Pharmacology, 2020Pulmonary fibrosis is a kind of pulmonary disorder with chronic inflammation and excessive collagen deposition, and its etiology is not clear. Interleukin (IL)-38 is a new member of IL-1 family cytokines, but its role in pulmonary fibrosis has not been elucidated.
Zhiwei Xu +4 more
semanticscholar +3 more sources
Interleukin‐38 inhibits adipogenesis and inflammatory cytokine production in 3T3‐L1 preadipocytes
Cell Biology International, 2020Interleukin‐38 (IL‐38) is a novel member of the IL‐1 cytokine family with anti‐inflammatory activity. However, its effect on adipogenesis and inflammatory cytokines secretion of adipocytes in vitro has not been reported. To address whether IL‐38 inhibits
Yan Li +4 more
semanticscholar +3 more sources
Interleukin-38 increases the insulin sensitivity in children with the type 2 diabetes.
International Immunopharmacology, 2020The prevalence of type 2 diabetes mellitus (DM) is increasing in the children population. It is well known that inflammation contributes to the type 2 DM pathogenesis. Interleukin 38 (IL-38) is one newly identified anti-inflammatory factor. Therefore, we
Y. Liu +4 more
semanticscholar +3 more sources
Interleukin-38 is elevated in inflammatory bowel diseases and suppresses intestinal inflammation.
Cytokine, 2020There has been no report investigating the role of IL-38 in inflammatory bowel diseases (IBD). Therefore, we investigated the expression of IL-38 in IBD patients and its role in regulating intestinal inflammation.
Cheng Xie +6 more
semanticscholar +3 more sources
Journal of Interferon & Cytokine Research, 2021
The aim of this study was to assess interleukin-1β (IL-1β), IL-1Ra, IL-36, and IL-38 levels together with hs-CRP levels in patients with different radiographic grades of knee osteoarthritis (OA) in comparison to healthy individuals.
Baver Akcan Duman +4 more
semanticscholar +4 more sources
The aim of this study was to assess interleukin-1β (IL-1β), IL-1Ra, IL-36, and IL-38 levels together with hs-CRP levels in patients with different radiographic grades of knee osteoarthritis (OA) in comparison to healthy individuals.
Baver Akcan Duman +4 more
semanticscholar +4 more sources
Plasma levels of interleukin-38 in healthy aging and in type 2 diabetes.
Diabetes Research and Clinical Practice, 2020Plasma levels of interleukin (IL)-38 were evaluated in patients with type 2 diabetes (T2DM) and healthy controls. Plasma IL-38 was higher in T2DM patients and positively related to waist/hip ratio, HbA1c, uric acid, liver function tests, triglycerides ...
Felicia Gurău +6 more
semanticscholar +3 more sources
Is Interleukin-38 a key player cytokine in atherosclerosis immune gene therapy?
Medical Hypotheses, 2019Atherosclerosis, a chronic inflammatory disease of the arteries associated with lipids and other metabolic alterations is a leading cause of death all around the world and its rate is raising as a result of unhealthy lifestyles.
A. Esmaeilzadeh +2 more
semanticscholar +3 more sources