Results 21 to 30 of about 349,293 (286)

Neutralizing anti-interleukin-1β antibodies modulate fetal blood–brain barrier function after ischemia

Neurobiology of Disease, 2015
We have previously shown that increases in blood–brain barrier permeability represent an important component of ischemia–reperfusion related brain injury in the fetus.
Xiaodi Chen, Grazyna B. Sadowska, Jiyong Zhang, Jeong-Eun Kim, Erin E. Cummings, Courtney A. Bodge, Yow-Pin Lim, Oleksandr Makeyev, Walter G. Besio, John Gaitanis, Steven W. Threlkeld, William A. Banks, Barbara S. Stonestreet   +12 more
doaj   +1 more source

Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium. [PDF]

, 2013
BACKGROUND: The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β).
AC Lin, AK Wann, AK Wann, AM Malone, AR Sartori-Cintra, BL Thoms, BL Thoms, CA Clement, CA Clement, CF Chang, CJ Haycraft, CJ Haycraft, CR Thoma, D Kong, D Zhu, DA Hoey, DM Katschinski, E Verghese, EN Pugacheva, F Oeffner, GJ Pazour, HA Praetorius, J Kim, JB Catterall, JC Kim, JE Bohonowych, JE Lafont, JF Reiter, JH Moyer, JH Ryu, JM Gerdes, JR Marszalek, JT Eggenschwiler, KC Corbit, KC Corbit, L Schneider, M Windheim, MA Lancaster, MF Bijlsma, NV Prodromou, P Jaakkola, PD Taulman, PV Tran, R Rohatgi, RD Thornton, S Abdul-Majeed, S Kim, S Massinen, S Murakami, S Proulx-Bonneau, S Yang, SH Low, SM Nauli, SN Greer, SR McGlashan, SR McGlashan, T Caspary, TY Besschetnova, X Xue, Y Li, YJ Jung   +60 more
core   +1 more source

Polymorphism of Interleukin-1β Gene in Children of Chernivtsi Region And its Impact on Development of Duodenal Ulcer

Zdorovʹe Rebenka, 2012
There were determined the genotype distribution frequency of interleukin-1β gene gene in promotor region -511C/T. It was defined that interleukin-1β-511*C allele and interleukin-1β-511С/C genotype increase the risk of duodenal ulcer in children ...
S.V. Sokolnyk
doaj   +1 more source

Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija, Dimova Cena, Evrosimoska Biljana, Stojanovska Vera, Muratovska Ilijana, Cetenović Bojana, Marković Dejan   +6 more
doaj   +1 more source

Study level of Interleukin-1β and Interleukin-2 in women infected with Trichomonas vaginalis parasite

AL-QADISIYAH MEDICAL JOURNAL, 2017
The study was conducted on 450 out patients and 30 healthy women, whom have visited the department of infertility at Al-Sadder medical city, Al-Zahra Hospital and in Najaf Province during the period from January till August, 2012. The infection with T.vaginalis in clinical suspected women determine by using the wet amount microscope,the infection women
Basima Sh. Al Gazali, Maysoon K. A .Al-Hadraawy, Haqi A .A .Al-fatlway   +2 more
openaire   +1 more source

Dexamethasone suppresses interleukin-1β-induced human β-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-κB transcriptional factor in A549 cells [PDF]

FEMS Immunology & Medical Microbiology, 2007
Human beta-defensin (HBD)-2 is an inducible antimicrobial peptide that plays an important role in innate immunity. Glucocorticoids, on the other hand, exert immunosuppressive and anti-inflammatory actions. We have previously reported that interleukin (IL)-1beta induces HBD-2 mRNA expression through the activation of nuclear factor-kappaB (NF-kappaB ...
Byeong-Churl Jang, Ki-Jo Lim, Min-Ho Suh, Jong-Gu Park, Seong-Il Suh   +4 more
openaire   +3 more sources

Colchicine therapy in acute coronary syndrome patients acts on caspase-1 to suppress NLRP3 inflammasome monocyte activation [PDF]

, 2016
Inflammasome activation, with subsequent release of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18, has recently been implicated in atherosclerosis-associated inflammation. This study aims to assess in acute coronary syndrome (ACS) patients (
Christina Bursill, Cloe A Payet, David S Celermajer, Gonzalo J Martínez, Jennifer Y Barraclough, Sanjay Patel, Stacy Robertson, † ‡, † ‡   +8 more
core   +1 more source

Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. [PDF]

PLoS ONE, 2015
The main objective of this study was to assess the in vitro effects of curcuminoids extract, hydrolyzed collagen and green tea extract in normal bovine chondrocytes and osteoarthritic human chondrocytes cultured in monolayer. This study also investigated
Fanny Comblain, Christelle Sanchez, Isabelle Lesponne, Marc Balligand, Samuel Serisier, Yves Henrotin   +5 more
doaj   +1 more source

The Regulation of Aggrecanase ADAMTS-4 Expression in Human Achilles Tendon and tendon-Derived Cells [PDF]

, 2008
Several members of the ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) family have been identified as aggrecanases, whose substrates include versican, the principal large proteoglycan in the tendon extracellular matrix.
Corps, Anthony N., Curry, Valerie A., Harrall, Rebecca L., Hazleman, Brian L., Jones, Gavin C., Riley, Graham P.   +5 more
core   +2 more sources

Impact of Proinflammatory Cytokines: (Interleukin 6, Interleukin 1α, and Interleukin 1β) on Biochemical Parameters in Severe Acute Respiratory Syndrome Coronavirus 2 Patients in Iraq

Biomedical and Biotechnology Research Journal, 2022
Background: The cytokine storm and specific biochemical results were both observed during Coronavirus disease 2019 (COVID-19) infection. The aim of this study was to see if there was any correlation between biochemical findings and cytokine levels ...
Ismael Raheem Al-Muhana, Mohanad Mohsin Ahmed, Ishaq Raheem Al-Muhana, Baraa Akeel AL-Hasan   +3 more
doaj   +1 more source