Results 31 to 40 of about 604,134 (278)

Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. [PDF]

PLoS ONE, 2015
The main objective of this study was to assess the in vitro effects of curcuminoids extract, hydrolyzed collagen and green tea extract in normal bovine chondrocytes and osteoarthritic human chondrocytes cultured in monolayer. This study also investigated
Fanny Comblain, Christelle Sanchez, Isabelle Lesponne, Marc Balligand, Samuel Serisier, Yves Henrotin   +5 more
doaj   +1 more source

Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D/bioreactor model [PDF]

, 2013
IntroductionThe present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs.MethodsNatriuretic peptide (Npr) 2 and 3 expression were compared in ...
Salter, Donald M, Salter, Donald M., Ramachandran, Manoj, Adrian J Hobbs, Hobbs, Adrian J., Ramachandran, M, Moyes, AJ, Amie J Moyes, Peake, Nicholas, Bader, Dan L, Bader, DL, Chowdhury, Tina T., Donald M Salter, Pramod Achan, Bader, Dan L., Peake, N, Su, N, Achan, P, Hobbs, AJ, Salter, DM, Nyan Su, Achan, Pramod, Nicholas Peake, Chowdhury, TT, Moyes, Amie J., Dan L Bader, Tina T Chowdhury, Su, Nyan, Chowdhury, Tina T, Hobbs, Adrian J, Moyes, Amie J, Manoj Ramachandran   +31 more
core   +1 more source

Intracerebral NMDA Injection Stimulates Production of Interleukin-1Β in Perinatal Rat Brain [PDF]

, 1996
Susceptibility to NMDA neurotoxicity peaks in the early postnatal period in rats. Although indirect evidence suggests that interleukin-1Β is a mediator of NMDA neurotoxicity in perinatal rats, direct confirmation of NMDA-induced interleukin-1Β production
Poole, S., Bristow, A. F., Tilders, F., S. Poole, A. F. Bristow, P. Hagan, Hagan, P., F. S. Silverstein, F. Tilders   +8 more
core   +1 more source

Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]

, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core   +1 more source

Interleukin‐1β Disruption Protects Male Mice From Heart Failure With Preserved Ejection Fraction Pathogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Heart failure with preserved ejection fraction (HFpEF) is a significant unmet need in cardiovascular medicine and remains an untreatable cardiovascular disease.
Balaji K. Srinivas, Aya Bourdi, Jacob D. O'Regan, Kumar D. Malavalli, Nour‐Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +6 more
doaj   +1 more source

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction [PDF]

, 2015
Background—Myocardial infarction (MI) is an ischemic wound that recruits millions of leukocytes. MI-associated blood leukocytosis correlates inversely with patient survival, yet the signals driving heightened leukocyte production after MI remain ...
Sun, Yuan, Heidt, Timo, Tricot, Benoit, Weissleder, Ralph, Swirski, Filip, Swirski, Filip K., Hulsmans, Maarten, Dutta, Partha, Libby, Peter, Courties, Gabriel, Iwamoto, Yoshiko, Nahrendorf, Matthias, Sager, Hendrik B., Sebas, Matthew, Wojtkiewicz, Gregory R.   +14 more
core   +1 more source

Regulation of electrolyte transport with IL-1β in rabbit distal colon

Mediators of Inflammation, 1995
Interletrkin-1β levels are elevated in inflammatory bowel disease. In this study the mechanism by which interleukin-1β affects electrolyte transport in the rabbit distal colon, was investigated.
F. R. Homaidan, H. Desai, L. Zhao, G. Broutman, R. Burakoff   +4 more
doaj   +1 more source

Assessment of salivary interleukin-1β (IL-1β), prostaglandin E2(PGE2) levels and pain intensity in children and adults during initial orthodontic treatment

Journal of Orthodontic Science, 2019
OBJECTIVES: To investigate pain intensity, interleukin-1β and prostaglandin E2 values in saliva during initial orthodontic treatment among varying age groups and their correlation between these mediators.
Amrit S Maan, Anand K Patil
doaj   +1 more source

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

Cell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Effects of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α ) on dopamine of the cerebral palsy

Asian Journal of Tropical Biotechnology, 2004
The caused of disability on cerebral palsy is unknown, but the human cerebral hypoxic, which affected to the motor cortex and motor pathways in the brain is believed cause of it. The major clinical manifestations are abnormality of movements and posture patterns. The immunity against the cerebral palsy (CP) is unknown, but interleukine-1β (IL-1β) and
openaire   +1 more source