Results 21 to 30 of about 604,134 (278)

Methylation-Dependent Gene Silencing Induced by Interleukin 1β via Nitric Oxide Production [PDF]

The Journal of Experimental Medicine, 1999
Interleukin (IL)-1β is a pleiotropic cytokine implicated in a variety of activities, including damage of insulin-producing cells, brain injury, or neuromodulatory responses. Many of these effects are mediated by nitric oxide (NO) produced by the induction of NO synthase (iNOS) expression. We report here that IL-1β provokes a marked repression of genes,
Hmadcha, Abdelkrim, Bedoya Bergua, Francisco Javier, Sobrino, Francisco, Pintado Sanjuán, Elizabeth   +3 more
openaire   +4 more sources

Study level of Interleukin-1β and Interleukin-2 in women infected with Trichomonas vaginalis parasite

AL-QADISIYAH MEDICAL JOURNAL, 2017
The study was conducted on 450 out patients and 30 healthy women, whom have visited the department of infertility at Al-Sadder medical city, Al-Zahra Hospital and in Najaf Province during the period from January till August, 2012. The infection with T.vaginalis in clinical suspected women determine by using the wet amount microscope,the infection women
Basima Sh. Al Gazali, Maysoon K. A .Al-Hadraawy, Haqi A .A .Al-fatlway   +2 more
openaire   +1 more source

Peptidoglycan and teichoic acid fromStaphylococcus epidermidisstimulate human monocytes to release tumour necrosis factor-α, interleukin-1β and interleukin-6 [PDF]

FEMS Immunology & Medical Microbiology, 1993
Cytokines play a major role in the pathophysiology of septic shock. In this study, human peripheral blood monocytes were stimulated with peptidoglycan and teichoic acid, purified from a strain of Staphylococcus epidermidis. Polymyxin B (PM-B) was added to avoid the effects of possible contamination with endotoxin.
E, Mattsson, L, Verhage, J, Rollof, A, Fleer, J, Verhoef, H, van Dijk   +5 more
openaire   +2 more sources

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages [PDF]

Journal of Biological Chemistry, 2015
Metformin, a frontline treatment for type II diabetes mellitus, decreases production of the pro-form of the inflammatory cytokine IL-1β in response to LPS in macrophages. We found that it specifically inhibited pro-IL-1β production, having no effect on TNF-α.
Beth Kelly, Gillian M. Tannahill, Michael P. Murphy, Luke A. J. O'Neill   +3 more
openaire   +4 more sources

Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]

PLoS ONE, 2012
Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao, Liaoliao Li, Daowei Lin, Zhiyi Zuo   +3 more
doaj   +1 more source

Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija, Dimova Cena, Evrosimoska Biljana, Stojanovska Vera, Muratovska Ilijana, Cetenović Bojana, Marković Dejan   +6 more
doaj   +1 more source

Impact of Proinflammatory Cytokines: (Interleukin 6, Interleukin 1α, and Interleukin 1β) on Biochemical Parameters in Severe Acute Respiratory Syndrome Coronavirus 2 Patients in Iraq

Biomedical and Biotechnology Research Journal, 2022
Background: The cytokine storm and specific biochemical results were both observed during Coronavirus disease 2019 (COVID-19) infection. The aim of this study was to see if there was any correlation between biochemical findings and cytokine levels ...
Ismael Raheem Al-Muhana, Mohanad Mohsin Ahmed, Ishaq Raheem Al-Muhana, Baraa Akeel AL-Hasan   +3 more
doaj   +1 more source

Interleukin-1β Promotes Repair of the CNS [PDF]

, 2001
Interleukin-1β (IL-1β) is a proinflammatory cytokine associated with the pathophysiology of demyelinating disorders such as multiple sclerosis and viral infections of the CNS.
Chaplin, David D., Matsushima, Glenn K., Jeffrey L. Mason, Suzuki, Kinuko, Kinuko Suzuki, Glenn K. Matsushima, Mason, Jeffrey L., David D. Chaplin   +7 more
core   +1 more source

Dexamethasone suppresses interleukin-1β-induced human β-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-κB transcriptional factor in A549 cells [PDF]

FEMS Immunology & Medical Microbiology, 2007
Human beta-defensin (HBD)-2 is an inducible antimicrobial peptide that plays an important role in innate immunity. Glucocorticoids, on the other hand, exert immunosuppressive and anti-inflammatory actions. We have previously reported that interleukin (IL)-1beta induces HBD-2 mRNA expression through the activation of nuclear factor-kappaB (NF-kappaB ...
Byeong-Churl Jang, Ki-Jo Lim, Min-Ho Suh, Jong-Gu Park, Seong-Il Suh   +4 more
openaire   +3 more sources

Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium. [PDF]

, 2013
BACKGROUND: The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β).
Wann, AK, Wann, Angus K.T., Chapple, JP, Knight, MM, Knight, Martin M., Thompson, CL, Thompson, Clare L., Chapple, J. Paul   +7 more
core   +1 more source