Results 291 to 300 of about 23,313,489 (418)

The interleukin-2 receptor.

Journal of Biological Chemistry, 1991
openaire   +3 more sources

Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/STAT5 signalling pathways

Immunology, 2012
Seon-Yeong Lee, M. Cho, H. Oh, J. Ryu, Min-jung Park, J. Jhun, Mi-Kyung Park, J. Stone, Ji‐hyun Ju, Sue‐Yun Hwang, Sung-Hwan Park, C. Surh, Ho‐Youn Kim   +12 more
semanticscholar   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

Advanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan, Xueman Chen, Huai Yu, Jianzhao Ruan, Jingliang Kang, Xiaoyu Nie, Yumei Cao, Su'an Tang, Changhai Ding   +8 more
wiley   +1 more source

Diagnostic value of soluble Interleukin-2 receptor in patients suffering neurosarcoidosis: A systematic review. [PDF]

J Cent Nerv Syst Dis
Chanpura A, Gupta RK, Sriwastava SK, Rahmig J.   +3 more
europepmc   +1 more source

Identification of lymphocyte integral membrane proteins as substrates for protein kinase C. Phosphorylation of the interleukin-2 receptor, class I HLA antigens, and T200 glycoprotein.

, 1986
Deborah A. Shackelford, Ian S. Trowbridge   +1 more
openalex   +1 more source

Interleukin-2 receptor signaling: at the interface between tolerance and immunity.

Immunity, 2010
T. Malek, I. Castro
semanticscholar   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Interleukin-2-mediated NF-κB-dependent mRNA splicing modulates interferon gamma protein production. [PDF]

EMBO Rep
Van Gelder RD, Gokhale NS, Genoyer E, Omelia DS, Anderson SK, Young HA, Savan R.   +6 more
europepmc   +1 more source