We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. [PDF]
Susanne J. Szabo +3 more
openalex +1 more source
[Cold stimulation promotes interleukin-4 secretion by mucosal-associated invariant T cells in the adipose tissue to promote adipose browning in mice]. [PDF]
X Ye, Yong Song, Yang Zhao, Donglin Zhu
openalex +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang +2 more
wiley +1 more source
Identification of the IgG1-induction factor (Interleukin 4)
Eva eSeverinson
doaj +1 more source
Correlation between the frequency of the infectious complications of abdominal surgery and the level of immune response to the surgical trauma [PDF]
Aim: to evaluate the correlations between the frequency of the infectious complications of abdominal surgery and the level of immune response to the surgery. Material and methods.
Korsakov I.N. +6 more
doaj
The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response [PDF]
The aim of this article is to review current literature on the response of soluble interleukin-6 receptor to exercise and identify a potential role for sIL-6R in skeletal muscle function.
Cockburn, Emma +4 more
core
Interleukin-4 transgenic mice develop glomerulosclerosis independent of immunoglobulin deposition [PDF]
Beate M. Rüger +5 more
openalex +1 more source
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source

