Decreased Expression of Leptin among Patients with Shoulder Stiffness
Shoulder stiffness (SS) is a disease that is fibroblastic and inflammatory in nature. Leptin is an adipokine-mediating the fibroblastic and inflammatory processes of various diseases.
Jih-Yang Ko +5 more
doaj +1 more source
CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction [PDF]
published_or_final_versio
Bi, J +9 more
core +1 more source
Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data. [PDF]
Chimeric antigen receptor (CAR) T-cell therapy has shown promise in the treatment of haematological cancers and is currently being investigated for solid tumours, including high-grade glioma brain tumours.
Abler, Daniel +13 more
core +2 more sources
Interleukin-25 Mediated Induction of Angiogenin-4 Is Interleukin-13 Dependent. [PDF]
The intestinal surface is directly exposed to both commensal microorganisms as well as pathogens with a single layer of epithelium separating luminal microorganisms from internal tissues.
Zannatun Noor +3 more
doaj +1 more source
Th2 Cytokines Increase the Expression of Fibroblast Growth Factor 21 in the Liver
Interleukin-4 (IL-4) and IL-13 are the major T helper 2 (Th2) cytokines, and they are involved in the regulation of metabolism in the adipose tissue. The liver contains diverse innate and adaptive immune cells, but it remains to be determined whether Th2
Seul-Gi Kang +9 more
doaj +1 more source
IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht +5 more
core +1 more source
Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine [PDF]
Background: The development of therapeutic vaccines requires thorough knowledge of potential hazards associated with long-term inactivation of self-proteins.
Foerster, John, Molęda, Aleksandra
core +2 more sources
The early diagnosis of preeclampsia, a key outlook in improving pregnancy outcomes, still remains elusive. The present study aimed to examine the interleukin-13 and interleukin-4 pathway potential in the early detection of preeclampsia as well as the ...
Aida Saadaty +4 more
doaj +1 more source
Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition [PDF]
Undernutrition in children is a pressing global health problem, manifested in part by impaired linear growth (stunting). Current nutritional interventions have been largely ineffective in overcoming stunting, emphasizing the need to obtain better ...
Ahern, Philip P. +13 more
core +2 more sources
Interleukin-13 (IL-13) Pathway [PDF]
Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T H 2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). It is also produced by activated eosinophils.
Ann, Kelly-Welch +2 more
openaire +2 more sources

