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Physiologic roles of interleukin-2, interleukin-4, and interleukin-7
Current Opinion in Hematology, 1996The use of gene targeting techniques has led to new insights into the physiologic function of lymphoid growth factors, their receptors, and associated signal transduction molecules in the formation and function of T and B cells. Mice rendered deficient for the growth factors interleukin-2 or interleukin-4 exhibit impairment in certain immune responses ...
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Regulation of Interleukin 4 Production and of Interleukin 4-Producing Cells
International Archives of Allergy and Immunology, 1992Interleukin 4 (IL-4) is a cytokine with a broad range of functions on immune cells including the stimulation of IgE synthesis by B cells. IL-4 is synthesized by freshly isolated T cells following appropriate stimulation with either lectins or antibodies against selected surface antigens.
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Gan to kagaku ryoho. Cancer & chemotherapy, 1994
Helper T cells can be divided into Th1 type cell which produces IL-2 and IFN-gamma and Th2 type cell which produces IL-4, IL-5, and IL-6. In general, cytokine has a pleiotropic action. Furthermore cytokines have redundancy in their action. IL-4 is a major product of Th 2 type cell and is an essential cytokine for IgE production, which is also induced ...
N, Nagai +3 more
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Helper T cells can be divided into Th1 type cell which produces IL-2 and IFN-gamma and Th2 type cell which produces IL-4, IL-5, and IL-6. In general, cytokine has a pleiotropic action. Furthermore cytokines have redundancy in their action. IL-4 is a major product of Th 2 type cell and is an essential cytokine for IgE production, which is also induced ...
N, Nagai +3 more
openaire +1 more source
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
Cancer Cell, 2022Yared Hailemichael +2 more
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
New England Journal of Medicine, 2021Anthony C Gordon +2 more
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