Results 191 to 200 of about 1,050,624 (355)

Inhibition of Interleukin-4- and CD40-induced IgE Germline Gene Promoter Activity by 2′-Aminoethoxy-modified Triplex-forming Oligonucleotides [PDF]

, 2001
Adrian M. Stütz, Jutta Horejs‐Hoeck, François Natt, Bernard Cuenoud, Maximilian Woisetschläger   +4 more
openalex   +1 more source

Data from Expression of Interleukin-4 Receptor Alpha in Human Pleural Mesothelioma Is Associated with Poor Survival and Promotion of Tumor Inflammation

, 2023
Bryan M. Burt, Andrew Bader, Daniel Winter, Scott J. Rodig, Raphael Bueno, David J. Sugarbaker   +5 more
openalex   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Erratum to "Interleukin-4-Mediated NLRP3 Inflammasome Activation in Microglia Contributes to Allergic Rhinitis via Central Sensitization". [PDF]

Research (Wash D C)
Lv H, Wang Y, Tan L, Xie Y, Liu P, Guan M, Cong J, Xu Y.   +7 more
europepmc   +1 more source

Intra-articular injection of interleukin-4 decreases nitric oxide production by chondrocytes and ameliorates subsequent destruction of cartilage in instability-induced osteoarthritis in rat knee joints [PDF]

, 2008
正則 依光
openalex  

Interleukin-4 regulates the interleukin-2 receptors on human peripheral blood B lymphocytes [PDF]

, 1991
Kazuhiro Tomizawa, Akitoshi Ishizaka, Katsura Kojima, Masahiro Nakanishi, Yukio Sakiyama, Shuzo Matsumoto   +5 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Neurons differentially upregulate type 2 immune cytokines and interleukin-4 receptor subtypes during neuroinflammation. [PDF]

Acta Neuropathol Commun
Domingues M, Gärtner Y, Hanuscheck N, Schmaul S, Zipp F, Vogelaar CF.   +5 more
europepmc   +1 more source

Mycobacterium tuberculosis Culture Filtrate Proteins plus CpG Oligodeoxynucleotides Confer Protection to Mycobacterium bovis BCG-Primed Mice by Inhibiting Interleukin-4 Secretion

, 2009
Denise Morais da Fonseca, Célio Lopes Silva, Pryscilla Fanini Wowk, Marina Oliveira e Paula, Simone G. Ramos, Cynthia Horn, G Marchal, Vânia Luiza Deperon Bonato   +7 more
openalex   +2 more sources

p38 Mitogen-activated Protein Kinase Regulates Interleukin-4-induced Gene Expression by Stimulating STAT6-mediated Transcription [PDF]

, 2002
Marko Pesu, Saara Aittomäki, Kati Takaluoma, Anssi Lagerstedt, Olli Silvennoinen   +4 more
openalex   +1 more source