Results 321 to 330 of about 9,696,955 (392)

Interleukin-6 levels and their haplotypes are associated with serological autoantibodies status and clinical activity in rheumatoid arthritis. [PDF]

Front Immunol
Flores-Castro MN, Falfán-Valencia R, Briceño O, Gutiérrez-Pérez IA, Zaragoza-García O, Pérez-Rubio G, Morales-Martínez C, Guzmán-Guzmán IP.   +7 more
europepmc   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Persistent systemic interleukin-6 elevation after community-acquired pneumonia is associated with one-year mortality. [PDF]

Respir Res
Piqueras M, González-Jiménez P, Latorre A, Mengot N, Tortosa-Carreres J, Gimeno Á, Picazos B, Porcar M, Menéndez R, Méndez R.   +9 more
europepmc   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

Lon peptidase 1 promotes proliferation and metastasis in breast cancer via interleukin 6 signaling. [PDF]

Discov Oncol
Gao Y, Duan C, Luan S, Wang X, Xu P, Jiao Y, Fu P, Zhao C.   +7 more
europepmc   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Interleukin-6 as the preferred prognostic factor in infection-complicated acute myeloid leukemia. [PDF]

Contemp Oncol (Pozn)
Bujko-Wasiak N, Kaźmierczak A, Lisak ŁD, Jędrzejrzak WW, Petrasz P, Zorga P, Brzeźniakiewicz-Janus K.   +6 more
europepmc   +1 more source

Integrative genetic and multi-omics analysis reveals the interleukin-6 receptor's role in recurrent spontaneous abortion. [PDF]

Front Immunol
Ma W, Gu Z, Lin Q, Cao M, Zhong J, Li X, Li H, Lin Y, Lin H, Xu M, Liu J, Du L, Song G.   +12 more
europepmc   +1 more source

Interleukin-6 extraction ratios during prolonged CytoSorb hemoadsorption depend on procedural blood flow. [PDF]

Front Med (Lausanne)
Gubensek J, Vajdic Trampuz B, Zrimsek M, Persic V.   +3 more
europepmc   +1 more source