Results 341 to 350 of about 9,696,955 (392)
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Interleukin-6-Producing Pheochromocytoma
Acta Haematologica, 1991A 42-year-old female with high fever and headache was admitted. Physical examination revealed hypertension, thrombocytosis with megakaryocytosis, hyperfibrinogenemia, and high level of serum noradrenaline. After operation of extramedullary pheochromocytoma, all symptoms disappeared and findings became normal.
K, Suzuki +6 more
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Role of Interleukin-6 in Development of Insulin Resistance and Type 2 Diabetes Mellitus.
Critical Reviews in Eukaryotic Gene Expression, 2017Interleukin-6 (IL-6) is a proinflammatory cytokine that decisively induces the development of insulin resistance and pathogenesis of type 2 diabetes mellitus (T2DM) through the generation of inflammation by controlling differentiation, migration ...
K. Rehman +5 more
semanticscholar +1 more source
Current Protocols in Immunology, 1996
AbstractInterleukin 6 (IL‐6) is a pluripotent cytokine with multiple effects on many different cell types. It is produced by a variety of cells in response to immunological and other stimuli. This unit describes a simple and sensitive assay for human, rat, rabbit, pig, and mouse IL‐6, based on IL‐6‐dependent proliferation of a murine B cell hybridoma ...
R P, Nordan, C D, Richards, J, Gauldie
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AbstractInterleukin 6 (IL‐6) is a pluripotent cytokine with multiple effects on many different cell types. It is produced by a variety of cells in response to immunological and other stimuli. This unit describes a simple and sensitive assay for human, rat, rabbit, pig, and mouse IL‐6, based on IL‐6‐dependent proliferation of a murine B cell hybridoma ...
R P, Nordan, C D, Richards, J, Gauldie
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Melanoma Research, 2012
Interleukin-6 (IL-6) is a pleiotropic immunomodulatory cytokine produced by various types of cells, including melanoma cells. IL-6 plays a major role in the pathogenesis and development of malignancies. It promotes tumour growth by inhibition of apoptosis and induces tumour angiogenesis. IL-6 is deregulated in many types of cancers, and increased serum
Hoejberg, Lise +2 more
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Interleukin-6 (IL-6) is a pleiotropic immunomodulatory cytokine produced by various types of cells, including melanoma cells. IL-6 plays a major role in the pathogenesis and development of malignancies. It promotes tumour growth by inhibition of apoptosis and induces tumour angiogenesis. IL-6 is deregulated in many types of cancers, and increased serum
Hoejberg, Lise +2 more
openaire +3 more sources
Interleukin-6 Inhibitor: Tocilizumab
2015Inhibitors of interleukin-6 (IL-6) are proteins which decrease the actions of the inflammatory cytokine, IL-6. Clinically, tocilizumab is the major inhibitor of IL-6. Several other proteins with IL-6 inhibitory actions (e.g., sirukumab) are being tested in clinical trials.
Pile, Kevin D. +2 more
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