Results 131 to 140 of about 80,628 (293)

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Single-cell transcriptome analysis of bronchoalveolar lavage during early SARS-CoV-2 infection

Microbiology Spectrum
The COVID-19 pandemic, triggered by the SARS-CoV-2 virus, has led to global consequences since its emergence in late 2019, impacting health, economies, and societies worldwide.
Sadia Akter, Mushtaq Ahmed, Dhiraj K. Singh, Kuldeep S. Chauhan, Deepak Kaushal, Shabaana A. Khader   +5 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Electropolymerized Aptasensor for Femtogram‐Level Cytokine Detection

Advanced Materials, EarlyView.
Electropolymerization of 3‐amino‐ʟ‐tyrosine creates ultrathin, smooth, and chemically robust pALT nanofilms with accessible carboxyl functionalities for direct aptamer immobilization. Integrated with fiber‐optic SPR and OECT platforms, these interfaces enable IL‐6 detection down to 100 fg mL−1 and provide a versatile route to bioelectronic sensing ...
Jiyao Yu, Renan Colucci, Rachel X. Shi, Qi Lu, Tommaso Marchesi D'Alvise, Ulrike Kraft, Christopher V. Synatschke, Tanja Weil   +7 more
wiley   +1 more source

Influence of excessive pro-inflammatory immune response on immunological parameters in women with early miscarriages

Инфекция и иммунитет
The study results showed that in the early pregnancy (up to 12 weeks) in women with a full-term pregnancy, but suffering from genital infections, changes occur in cellular immune arm.
V. A. Aleynik, Mokhigul A. Zhuraeva, K. O. Mukhitdinova, S. M. Babich, X. N. Negmatshayeva   +4 more
doaj   +1 more source

The Relationship Between Serum Levels of Interleukins 6, 8, 10 and Clinical Outcome in Patients With Severe Traumatic Brain Injury [PDF]

, 2015
Background: Clinical outcome in patients with severe traumatic brain injury (TBI) depends on both primary and secondary brain injuries. Neuroinflammation is an important secondary mechanism, which occurs by releasing interleukins (ILs).
Hosseinpour, M., Dehnadi Moghaddam, A., Razzaghi, A., Mohtasham-Amiri, Z., Yousefzadeh-Chabok, S., Saneei, Z., Kazemnezhad-Leili, E., Kouchakinejad-Eramsadati, L.   +7 more
core  

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Interleukins and Cardiovascular Disease

Interleukins are important inflammatory cytokines involved in cardiovascular (CV) disease (CVD) pathogenesis, particularly in atherosclerosis, by regulating inflammation, endothelial dysfunction, plaque formation,
Antonis S. Manolis, Theodora A. Manolis, Antonis A. Manolis   +2 more
core   +1 more source

Predictive Biomarkers in Carotid Atherosclerosis: Interleukins 6, 8, and 10

, 2023
Stroke attained its status as the third leading cause of death and disability combined in 2019. During that same year, over 62% of all strokes that occurred globally were ischemic, and approximately 10-20% of ischemic strokes have an etiology of carotid ...
Woller, Katherine Elizabeth Kyllikki
core